The erythrocyte protoporphyrin in chronic renal failure

The erythrocyte protoporphyrin in chronic renal failure

The erythrocyte protoporphyrin concentration in 63 patients suffering from chronic renal failure was estimated and found to be significantly decreased when compared to healthy subjects. There was a negative correlation between the decrease of the erythrocyte protoporphyrin and the blood urea and hae...

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Veröffentlicht in:Clinica chimica acta 1975-01, Vol.65 (3), p.389-392
Hauptverfasser: Vlassopoulos, K., Melissinos, K., Drivas, G.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Aged
Erythrocytes - metabolism
Female
Hematocrit
Humans
Kidney Failure, Chronic - blood
Male
Middle Aged
Porphyrins - blood
Protoporphyrins - blood
Renal Dialysis
Uremia - metabolism
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Zusammenfassung:The erythrocyte protoporphyrin concentration in 63 patients suffering from chronic renal failure was estimated and found to be significantly decreased when compared to healthy subjects. There was a negative correlation between the decrease of the erythrocyte protoporphyrin and the blood urea and haematocrit. Following haemodialysis the concentration of erythrocyte protoporphyrin was reduced but not significantly so. It is proposed that uraemia or insufficiency of erythropoietin could affect erythroblasts and young red cells impairing haem synthesis.
ISSN:0009-8981
1873-3492
DOI:10.1016/0009-8981(75)90265-X