Relation of Cathartic Activity to Structural Modifications of Ricinoleic Acid of Castor Oil

Castor oil and certain of its derivatives were tested in rats to elucidate the specific structural configuration of castor oil responsible for its cathartic action. The results indicate that the hydroxyl function on carbon-12 and the double bond between carbons 9 and 10 of the ricinoleic acid moiety...

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Veröffentlicht in:Journal of pharmaceutical sciences 1962-10, Vol.51 (10), p.999-1002
Hauptverfasser: Masri, M.S., Goldblatt, L.A., DeEds, F., Kohler, G.O.
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Sprache:eng
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