Immunosensing by colorimetric darkfield microscopy of individual gold nanoparticle-conjugates

A new (generic) sensor platform introduced using gold colorimetric data showed that binding events of individual particles could be discerned for about 40% of the available binding sites while reference data showed less than 0.05% binding. Endpoint SEM images of the sample and reference binding coup...

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Veröffentlicht in:Sensors and actuators. B, Chemical Chemical, 2010-10, Vol.150 (2), p.529-536
Hauptverfasser: Ungureanu, Felicia, Wasserberg, Dorothee, Yang, Ni, Verdoold, Remco, Kooyman, Rob P.H.
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container_end_page 536
container_issue 2
container_start_page 529
container_title Sensors and actuators. B, Chemical
container_volume 150
creator Ungureanu, Felicia
Wasserberg, Dorothee
Yang, Ni
Verdoold, Remco
Kooyman, Rob P.H.
description A new (generic) sensor platform introduced using gold colorimetric data showed that binding events of individual particles could be discerned for about 40% of the available binding sites while reference data showed less than 0.05% binding. Endpoint SEM images of the sample and reference binding couples corroborate our findings.
doi_str_mv 10.1016/j.snb.2010.08.044
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source Elsevier ScienceDirect Journals Complete
subjects Actuators
Affinity constant
Binding
Colorimetric darkfield microscopy
Colorimetry
Gold
Gold nanoparticles
Immunosensor
Nanocomposites
Nanostructure
Parallel detection
Sensors
title Immunosensing by colorimetric darkfield microscopy of individual gold nanoparticle-conjugates
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