Adaptation of conduit artery vascular smooth muscle tone to induced hypertension

We studied the changes in vascular smooth muscle (VSM) cell tone during the adaptation of rat common carotids to induced hypertension. Hypertension was induced in 8 week old male Wistar rats by total ligation of the aorta between the two kidneys. Mean blood pressure increased abruptly from 92 +/- 2m...

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Veröffentlicht in:	Annals of biomedical engineering 2002-07, Vol.30 (7), p.905-916
Hauptverfasser:	Fridez, P, Makino, A, Kakoi, D, Miyazaki, H, Meister, J J, Hayashi, K, Stergiopulos, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation Adaptation, Physiological - physiology Animals Blood Pressure Blood vessels Carotid Artery, Common - physiopathology Carotid Artery, Common - surgery Elasticity Hypertension Hypertension - physiopathology Male Models, Cardiovascular Muscle Contraction Muscle Tonus Muscle, Smooth, Vascular - physiopathology Muscular system Rats Rats, Wistar Reference Values Rodents Sensitivity and Specificity Stress, Mechanical Vascular Resistance
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