A temperature-sensitive mutation affecting the mammalian 60 S ribosome

A temperature-sensitive Chinese hamster cell mutant, ts14, is unable to synthesize protein in tissue culture at 39 degrees. That mutant's protein biosynthetic machinery has been characterized in cell-free, biologically active extracts. Similar to the mutant's phenotype in tissue culture, t...

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Veröffentlicht in:	The Journal of biological chemistry 1975-11, Vol.250 (22), p.8618-8623
Hauptverfasser:	Haralson, M A, Roufa, D J
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Genetic Complementation Test Mutation Polyribosomes - metabolism Protein Biosynthesis Ribosomal Proteins - metabolism Ribosomes - metabolism RNA, Messenger - metabolism Temperature
Online-Zugang:	Volltext
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