Studies on Nucleosides and Nucleotides. V. Ultraviolet Spectrophotometric Studies on Pyrimidine Nucleosides and Isopyrimidine Nucleosides
Ultraviolet absorption spectra of pyrimidine and isopyrimidine nucleosides were compared and their difference was examined. 1-(β-D-glucopyranosyl) uracil and 3-(β-D-glucopyranosyl) uracil show practically the same spectra in the neutral region while their spectra are clearly different in alkaline so...
Gespeichert in:
| Veröffentlicht in: | Chemical & pharmaceutical bulletin 1962/04/25, Vol.10(4), pp.320-327 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 327 |
|---|---|
| container_issue | 4 |
| container_start_page | 320 |
| container_title | Chemical & pharmaceutical bulletin |
| container_volume | 10 |
| creator | Sano, Mitsuji |
| description | Ultraviolet absorption spectra of pyrimidine and isopyrimidine nucleosides were compared and their difference was examined. 1-(β-D-glucopyranosyl) uracil and 3-(β-D-glucopyranosyl) uracil show practically the same spectra in the neutral region while their spectra are clearly different in alkaline solution. The spectra of 1- and 3-(β-D-glucopyranosyl)-2-thiouracils are different in both neutral and alkaline regions, and the spectra in neutral region seemed to be somewhat lacking in uniformity. These facts were found to be true in the case of thymines instead of uracils or in the presence of ribosyl group instead of glucosyl group. It follows that pyrimidine and isopyrimidine nucleosides could clearly be differentiated from their ultraviolet absorption spectra, especially from those taken in alkaline solution. |
| doi_str_mv | 10.1248/cpb.10.320 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_83048983</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3131147641</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3770-77b2d43291daeca898f891b9af78cfe0890baa6d02b55ae44a05a7b8cc51c3c53</originalsourceid><addsrcrecordid>eNptkV1rFDEUhoNY7Fq98QfIgOCFMOvJ1ya5lMWPQqlCrbdDJnPGZpmdjElG6E_wX5txF1uqN8k5nIeHk7yEvKCwpkzot25q16XmDB6RFeVC1ZIx_pisAMDUjG_4KXma0g6ASVD8CTmlQpiN0bAiv67y3HlMVRiry9kNGJLvSmvH7tjnpV9X39bV9ZCj_enDgLm6mtDlGKabkMMec_Suumf6chv93nd-xH-k5ylM_50-Iye9HRI-P95n5PrD-6_bT_XF54_n23cXteNKQa1UyzrBmaGdRWe10b02tDW2V9r1CNpAa-2mA9ZKaVEIC9KqVjsnqeNO8jPy-uCdYvgxY8rN3ieHw2BHDHNqNAdRrLyArx6AuzDHsezWUCHNRijFoFBvDpSLIaWIfTOV19l421BolniaEs9S8z_wy6NybvfY3aHHPAqwPQC7lO13_AvYmH35qcVFjdSLTxyOor2b3tjY4Mh_A9lbpZk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1459647720</pqid></control><display><type>article</type><title>Studies on Nucleosides and Nucleotides. V. Ultraviolet Spectrophotometric Studies on Pyrimidine Nucleosides and Isopyrimidine Nucleosides</title><source>J-STAGE Free</source><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Free Full-Text Journals in Chemistry</source><creator>Sano, Mitsuji</creator><creatorcontrib>Sano, Mitsuji</creatorcontrib><description>Ultraviolet absorption spectra of pyrimidine and isopyrimidine nucleosides were compared and their difference was examined. 1-(β-D-glucopyranosyl) uracil and 3-(β-D-glucopyranosyl) uracil show practically the same spectra in the neutral region while their spectra are clearly different in alkaline solution. The spectra of 1- and 3-(β-D-glucopyranosyl)-2-thiouracils are different in both neutral and alkaline regions, and the spectra in neutral region seemed to be somewhat lacking in uniformity. These facts were found to be true in the case of thymines instead of uracils or in the presence of ribosyl group instead of glucosyl group. It follows that pyrimidine and isopyrimidine nucleosides could clearly be differentiated from their ultraviolet absorption spectra, especially from those taken in alkaline solution.</description><identifier>ISSN: 0009-2363</identifier><identifier>EISSN: 1347-5223</identifier><identifier>DOI: 10.1248/cpb.10.320</identifier><identifier>PMID: 14496980</identifier><language>eng</language><publisher>Japan: The Pharmaceutical Society of Japan</publisher><subject>Nucleosides - chemistry ; Nucleotides - chemistry ; Old Medline ; Pyrimidine Nucleosides ; Spectrophotometry, Ultraviolet</subject><ispartof>Chemical and Pharmaceutical Bulletin, 1962/04/25, Vol.10(4), pp.320-327</ispartof><rights>The Pharmaceutical Society of Japan</rights><rights>Copyright Japan Science and Technology Agency 1962</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3770-77b2d43291daeca898f891b9af78cfe0890baa6d02b55ae44a05a7b8cc51c3c53</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1877,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14496980$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sano, Mitsuji</creatorcontrib><title>Studies on Nucleosides and Nucleotides. V. Ultraviolet Spectrophotometric Studies on Pyrimidine Nucleosides and Isopyrimidine Nucleosides</title><title>Chemical & pharmaceutical bulletin</title><addtitle>Chem. Pharm. Bull.</addtitle><description>Ultraviolet absorption spectra of pyrimidine and isopyrimidine nucleosides were compared and their difference was examined. 1-(β-D-glucopyranosyl) uracil and 3-(β-D-glucopyranosyl) uracil show practically the same spectra in the neutral region while their spectra are clearly different in alkaline solution. The spectra of 1- and 3-(β-D-glucopyranosyl)-2-thiouracils are different in both neutral and alkaline regions, and the spectra in neutral region seemed to be somewhat lacking in uniformity. These facts were found to be true in the case of thymines instead of uracils or in the presence of ribosyl group instead of glucosyl group. It follows that pyrimidine and isopyrimidine nucleosides could clearly be differentiated from their ultraviolet absorption spectra, especially from those taken in alkaline solution.</description><subject>Nucleosides - chemistry</subject><subject>Nucleotides - chemistry</subject><subject>Old Medline</subject><subject>Pyrimidine Nucleosides</subject><subject>Spectrophotometry, Ultraviolet</subject><issn>0009-2363</issn><issn>1347-5223</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1962</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkV1rFDEUhoNY7Fq98QfIgOCFMOvJ1ya5lMWPQqlCrbdDJnPGZpmdjElG6E_wX5txF1uqN8k5nIeHk7yEvKCwpkzot25q16XmDB6RFeVC1ZIx_pisAMDUjG_4KXma0g6ASVD8CTmlQpiN0bAiv67y3HlMVRiry9kNGJLvSmvH7tjnpV9X39bV9ZCj_enDgLm6mtDlGKabkMMec_Suumf6chv93nd-xH-k5ylM_50-Iye9HRI-P95n5PrD-6_bT_XF54_n23cXteNKQa1UyzrBmaGdRWe10b02tDW2V9r1CNpAa-2mA9ZKaVEIC9KqVjsnqeNO8jPy-uCdYvgxY8rN3ieHw2BHDHNqNAdRrLyArx6AuzDHsezWUCHNRijFoFBvDpSLIaWIfTOV19l421BolniaEs9S8z_wy6NybvfY3aHHPAqwPQC7lO13_AvYmH35qcVFjdSLTxyOor2b3tjY4Mh_A9lbpZk</recordid><startdate>196204</startdate><enddate>196204</enddate><creator>Sano, Mitsuji</creator><general>The Pharmaceutical Society of Japan</general><general>Japan Science and Technology Agency</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>196204</creationdate><title>Studies on Nucleosides and Nucleotides. V. Ultraviolet Spectrophotometric Studies on Pyrimidine Nucleosides and Isopyrimidine Nucleosides</title><author>Sano, Mitsuji</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3770-77b2d43291daeca898f891b9af78cfe0890baa6d02b55ae44a05a7b8cc51c3c53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1962</creationdate><topic>Nucleosides - chemistry</topic><topic>Nucleotides - chemistry</topic><topic>Old Medline</topic><topic>Pyrimidine Nucleosides</topic><topic>Spectrophotometry, Ultraviolet</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sano, Mitsuji</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical & pharmaceutical bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sano, Mitsuji</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Studies on Nucleosides and Nucleotides. V. Ultraviolet Spectrophotometric Studies on Pyrimidine Nucleosides and Isopyrimidine Nucleosides</atitle><jtitle>Chemical & pharmaceutical bulletin</jtitle><addtitle>Chem. Pharm. Bull.</addtitle><date>1962-04</date><risdate>1962</risdate><volume>10</volume><issue>4</issue><spage>320</spage><epage>327</epage><pages>320-327</pages><issn>0009-2363</issn><eissn>1347-5223</eissn><abstract>Ultraviolet absorption spectra of pyrimidine and isopyrimidine nucleosides were compared and their difference was examined. 1-(β-D-glucopyranosyl) uracil and 3-(β-D-glucopyranosyl) uracil show practically the same spectra in the neutral region while their spectra are clearly different in alkaline solution. The spectra of 1- and 3-(β-D-glucopyranosyl)-2-thiouracils are different in both neutral and alkaline regions, and the spectra in neutral region seemed to be somewhat lacking in uniformity. These facts were found to be true in the case of thymines instead of uracils or in the presence of ribosyl group instead of glucosyl group. It follows that pyrimidine and isopyrimidine nucleosides could clearly be differentiated from their ultraviolet absorption spectra, especially from those taken in alkaline solution.</abstract><cop>Japan</cop><pub>The Pharmaceutical Society of Japan</pub><pmid>14496980</pmid><doi>10.1248/cpb.10.320</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0009-2363 |
| ispartof | Chemical and Pharmaceutical Bulletin, 1962/04/25, Vol.10(4), pp.320-327 |
| issn | 0009-2363 1347-5223 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83048983 |
| source | J-STAGE Free; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Free Full-Text Journals in Chemistry |
| subjects | Nucleosides - chemistry Nucleotides - chemistry Old Medline Pyrimidine Nucleosides Spectrophotometry, Ultraviolet |
| title | Studies on Nucleosides and Nucleotides. V. Ultraviolet Spectrophotometric Studies on Pyrimidine Nucleosides and Isopyrimidine Nucleosides |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-21T22%3A56%3A52IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Studies%20on%20Nucleosides%20and%20Nucleotides.%20V.%20Ultraviolet%20Spectrophotometric%20Studies%20on%20Pyrimidine%20Nucleosides%20and%20Isopyrimidine%20Nucleosides&rft.jtitle=Chemical%20&%20pharmaceutical%20bulletin&rft.au=Sano,%20Mitsuji&rft.date=1962-04&rft.volume=10&rft.issue=4&rft.spage=320&rft.epage=327&rft.pages=320-327&rft.issn=0009-2363&rft.eissn=1347-5223&rft_id=info:doi/10.1248/cpb.10.320&rft_dat=%3Cproquest_cross%3E3131147641%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1459647720&rft_id=info:pmid/14496980&rfr_iscdi=true |