Steroid-binding properties of corticosteroid receptors in different target tissues of the rat

Specific corticosteroid binding receptors, characterized by high affinity and low capacity, were demonstrated in the cytoplasm of the liver, the thymus and the diaphragm of adult male rats. Corticosterone metabolite without biological activity is not bound by these receptors. The receptors in the liver cytoplasm appear to be similar to those in the thymus cytoplasm, an assumption based on similarities of corticosteroid binding properties.