Microbial models of mammalian metabolism. O-Dealkylation of 10,11-dimethoxyaporphine

Microbial transformations of 10,11-dimethoxyaporphine were studied to determine the potential of microorganisms to produce monomethoxyaporphines. Ten microorganisms were identified as being capable of yielding apocodeine and/or isoapocodeine as the major metabolite in 24 and 20% yield, respectively....

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Veröffentlicht in:	Journal of medicinal chemistry 1975-08, Vol.18 (8), p.791-794
Hauptverfasser:	Rosazza, J. P, Stocklinski, A. W, Gustafson, M. A, Adrian, J, Smith, R. V
Format:	Artikel
Sprache:	eng
Schlagworte:	Aporphines - metabolism Dealkylation Fermentation Microsporum - metabolism Mitosporic Fungi - metabolism Models, Biological Mucor - metabolism Mucorales - metabolism Penicillium - metabolism Streptomyces - metabolism
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