The application of electron microscopy and cellular biochemistry to the autopsy. Observations on cellular changes in human shock
A method based on the utilization of electron microscopy, morphometric analysis, tissue culture, and biochemical analysis in the study of human autopsies is described. In this method rapid sampling immediately following somatic death is conducted in order to make meaningful the application of such t...
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| Veröffentlicht in: | Human pathology 1975, Vol.6 (4), p.499-516 |
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| container_end_page | 516 |
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| container_issue | 4 |
| container_start_page | 499 |
| container_title | Human pathology |
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| creator | Trump, B F Valigorsky, J M Jones, R T Mergner, W J Garcia, J H Cowley, R A |
| description | A method based on the utilization of electron microscopy, morphometric analysis, tissue culture, and biochemical analysis in the study of human autopsies is described. In this method rapid sampling immediately following somatic death is conducted in order to make meaningful the application of such techniques. In addition to describing the procedure, we present some new findings relating to cellular changes associated with shock. As in cellular pathobiology, it is of utmost importance that ultrastructural changes be correlated with alterations in chemistry and function. |
| doi_str_mv | 10.1016/s0046-8177(75)80068-2 |
| format | Article |
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Observations on cellular changes in human shock</title><title>Human pathology</title><addtitle>Hum Pathol</addtitle><description>A method based on the utilization of electron microscopy, morphometric analysis, tissue culture, and biochemical analysis in the study of human autopsies is described. In this method rapid sampling immediately following somatic death is conducted in order to make meaningful the application of such techniques. In addition to describing the procedure, we present some new findings relating to cellular changes associated with shock. As in cellular pathobiology, it is of utmost importance that ultrastructural changes be correlated with alterations in chemistry and function.</description><subject>Adolescent</subject><subject>Adrenal Glands - ultrastructure</subject><subject>Adult</subject><subject>Aged</subject><subject>Autolysis</subject><subject>Autopsy</subject><subject>Brain - ultrastructure</subject><subject>Female</subject><subject>Histocytochemistry</subject><subject>Humans</subject><subject>Infant</subject><subject>Kidney - ultrastructure</subject><subject>Kidney Tubules - ultrastructure</subject><subject>Liver - ultrastructure</subject><subject>Lung - ultrastructure</subject><subject>Male</subject><subject>Microscopy, Electron</subject><subject>Middle Aged</subject><subject>Muscles - ultrastructure</subject><subject>Myocardium - ultrastructure</subject><subject>Pancreas - ultrastructure</subject><subject>Shock - pathology</subject><issn>0046-8177</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1975</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kDFPwzAUhD2ASin8hEqeEAwpdhLHzogqCkiVunSPXuxXEkjiYDtI2fjppFB1utPp3qfTI2TJ2Yoznj16xtIsUlzKeykeFGOZiuILMj_HV-Ta-w_GOBepmJHZpCyOxZz87Cuk0PdNrSHUtqP2QLFBHdzk21o767XtRwqdoRqbZmjA0bK2usK29sGNNFgajowh2N6PK7orPbrvP5inE-R8pSvo3tHTuqPV0EJHfWX15w25PEDj8fakC7LfPO_Xr9F29_K2ftpGOs5UiBKNkGCOSiMzkCieCJUY0FKKPDY5CMZ1afKUp5yxQ2k0L-NMApYyyySHZEHu_rG9s18D-lBM84_ToEM7-ELFuVRCsKm4PBWHskVT9K5uwY3F6WPJLwqab7Y</recordid><startdate>1975</startdate><enddate>1975</enddate><creator>Trump, B F</creator><creator>Valigorsky, J M</creator><creator>Jones, R T</creator><creator>Mergner, W J</creator><creator>Garcia, J H</creator><creator>Cowley, R A</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>1975</creationdate><title>The application of electron microscopy and cellular biochemistry to the autopsy. Observations on cellular changes in human shock</title><author>Trump, B F ; Valigorsky, J M ; Jones, R T ; Mergner, W J ; Garcia, J H ; Cowley, R A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c268t-3cea3e9e8ce0da3813583dac77592d9a501cbd9414100fbdc1b267aeb76671a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1975</creationdate><topic>Adolescent</topic><topic>Adrenal Glands - ultrastructure</topic><topic>Adult</topic><topic>Aged</topic><topic>Autolysis</topic><topic>Autopsy</topic><topic>Brain - ultrastructure</topic><topic>Female</topic><topic>Histocytochemistry</topic><topic>Humans</topic><topic>Infant</topic><topic>Kidney - ultrastructure</topic><topic>Kidney Tubules - ultrastructure</topic><topic>Liver - ultrastructure</topic><topic>Lung - ultrastructure</topic><topic>Male</topic><topic>Microscopy, Electron</topic><topic>Middle Aged</topic><topic>Muscles - ultrastructure</topic><topic>Myocardium - ultrastructure</topic><topic>Pancreas - ultrastructure</topic><topic>Shock - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Trump, B F</creatorcontrib><creatorcontrib>Valigorsky, J M</creatorcontrib><creatorcontrib>Jones, R T</creatorcontrib><creatorcontrib>Mergner, W J</creatorcontrib><creatorcontrib>Garcia, J H</creatorcontrib><creatorcontrib>Cowley, R A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Human pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Trump, B F</au><au>Valigorsky, J M</au><au>Jones, R T</au><au>Mergner, W J</au><au>Garcia, J H</au><au>Cowley, R A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The application of electron microscopy and cellular biochemistry to the autopsy. Observations on cellular changes in human shock</atitle><jtitle>Human pathology</jtitle><addtitle>Hum Pathol</addtitle><date>1975</date><risdate>1975</risdate><volume>6</volume><issue>4</issue><spage>499</spage><epage>516</epage><pages>499-516</pages><issn>0046-8177</issn><abstract>A method based on the utilization of electron microscopy, morphometric analysis, tissue culture, and biochemical analysis in the study of human autopsies is described. In this method rapid sampling immediately following somatic death is conducted in order to make meaningful the application of such techniques. In addition to describing the procedure, we present some new findings relating to cellular changes associated with shock. As in cellular pathobiology, it is of utmost importance that ultrastructural changes be correlated with alterations in chemistry and function.</abstract><cop>United States</cop><pmid>1150225</pmid><doi>10.1016/s0046-8177(75)80068-2</doi><tpages>18</tpages></addata></record> |
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| identifier | ISSN: 0046-8177 |
| ispartof | Human pathology, 1975, Vol.6 (4), p.499-516 |
| issn | 0046-8177 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Adolescent Adrenal Glands - ultrastructure Adult Aged Autolysis Autopsy Brain - ultrastructure Female Histocytochemistry Humans Infant Kidney - ultrastructure Kidney Tubules - ultrastructure Liver - ultrastructure Lung - ultrastructure Male Microscopy, Electron Middle Aged Muscles - ultrastructure Myocardium - ultrastructure Pancreas - ultrastructure Shock - pathology |
| title | The application of electron microscopy and cellular biochemistry to the autopsy. Observations on cellular changes in human shock |
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