Long-term follow-up for immunity after monovalent or combined live measles, mumps, and rubella virus vaccines

Long-term follow-up for immunity after monovalent or combined live measles, mumps, and rubella virus vaccines

Antibody in human subjects persisted without substantial decline for 8 years after mumps vaccine (Jeryl Lynn), for 6 years after measles (Attenuvax), for 5 1/2 years after rubella vaccine (HPV-77 duck), for 5 years after measles-mumps-rubella and mumps-rubella combined vaccines, for 4 years after me...

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Veröffentlicht in:Pediatrics (Evanston) 1975-09, Vol.56 (3), p.380-387
Hauptverfasser: Weibel, R E, Buynak, E B, McLean, A A, Hilleman, M R
Format: Artikel
Sprache:eng
Schlagworte:
Antibody Formation
Child, Preschool
Drug Stability
Follow-Up Studies
Humans
Measles Vaccine
Mumps Vaccine
Pennsylvania
Rubella Vaccine
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container_title Pediatrics (Evanston)
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creator Weibel, R E
Buynak, E B
McLean, A A
Hilleman, M R
description Antibody in human subjects persisted without substantial decline for 8 years after mumps vaccine (Jeryl Lynn), for 6 years after measles (Attenuvax), for 5 1/2 years after rubella vaccine (HPV-77 duck), for 5 years after measles-mumps-rubella and mumps-rubella combined vaccines, for 4 years after measles and rubella, and for 2 years after measles-mumps vaccines, the longest periods tested. Protective immunity against mumps illness persisted through the eighth year. The patterns for antibody following vaccination parallel those for natural infection and indicate that immunity will be lasting. Subclinical reinfection evidenced by antibody increase was commonly seen in persons who had been vaccinated, much as follows the natural infection.
doi_str_mv 10.1542/peds.56.3.380
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source MEDLINE; EZB-FREE-00999 freely available EZB journals
subjects Antibody Formation
Child, Preschool
Drug Stability
Follow-Up Studies
Humans
Measles Vaccine
Mumps Vaccine
Pennsylvania
Rubella Vaccine
title Long-term follow-up for immunity after monovalent or combined live measles, mumps, and rubella virus vaccines
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