Inhibitors of nucleoside transport. Structure-activity study using human erythrocytes

The passage of nucleosides across the plasma membrane of erythrocytes is a membrane-mediated process which is strongly inhibited by derivatives of 9-beta-D-ribofuranosylpurine (1) with S, O, or N atoms at the purine 6 position bearing variously substituted arylalkyl groups. In this structure-activit...

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Veröffentlicht in:Journal of medicinal chemistry 1975-10, Vol.18 (10), p.968-973
Hauptverfasser: Paul, Brajeswar, Chen, Marianne F, Paterson, Alan R. P
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Sprache:eng
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