Calculation of hydrophobic constant (log P) from .pi. and f constants

The highest level of confidence can be placed in calculated log P values when (1) the log P of a parent solute is known, (2) pi constants for the required substituent(s) are available, and (3) the substituents either do not have an effect on groups already present in the parent or else this effect h...

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Veröffentlicht in:	Journal of medicinal chemistry 1975-09, Vol.18 (9), p.865-868
Hauptverfasser:	Leo, A, Jow, P. Y. C, Silipo, C, Hansch, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkenes Chemical Phenomena Chemistry, Physical Kinetics Mathematics Solubility
Online-Zugang:	Volltext
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