Modulation of Stimulated Acid Secretion by Dibutyryl Cyclic Amp in the Dog Stomach

An in vivo canine gastric chamber preparation was used to determine cffects of exogenous cyclic AMP and dibutyryl cyclic AMP on histamine-driven acid secretion and the role of blood flow in these responses. Histamine was infused intravenously at a submaximal rate (1.2 μg/kg-min) followed by the intr...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 1975-07, Vol.69 (1), p.285-288
Hauptverfasser:	Bowen, John C., Pawlik, Wieslaw, Kuo, Y.M., Williams, David, Shanbour, Linda L., Jacobson, Eugene D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminopyrine - metabolism Animals Bucladesine - administration & dosage Bucladesine - pharmacology Cyclic AMP - administration & dosage Cyclic AMP - pharmacology Dogs Electrophysiology Female Gastric Juice - secretion Gastric Mucosa - blood supply Gastric Mucosa - drug effects Histamine - administration & dosage Histamine - pharmacology Infusions, Parenteral Male Metabolic Clearance Rate Regional Blood Flow - drug effects Stimulation, Chemical
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