Lipolytic Action of Human Chorionic Somatomammotropin

Human chorionic somatomammotropin extracted and purified from placenta at term was proved to have a lipolytic action in the epididymal fat pad of rats. The following mechanism appears to be involved in the lipolytic action of the hormone; human chorionic somatomammotropin activates adenyl cyclase, t...

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Veröffentlicht in:Endocrinologia Japonica 1975, Vol.22(2), pp.123-129
Hauptverfasser: MOCHIZUKI, MATSUTO, MORIKAWA, HAJIME, OHGA, YUZOH, TOJO, SHIMPEI
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container_issue 2
container_start_page 123
container_title Endocrinologia Japonica
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creator MOCHIZUKI, MATSUTO
MORIKAWA, HAJIME
OHGA, YUZOH
TOJO, SHIMPEI
description Human chorionic somatomammotropin extracted and purified from placenta at term was proved to have a lipolytic action in the epididymal fat pad of rats. The following mechanism appears to be involved in the lipolytic action of the hormone; human chorionic somatomammotropin activates adenyl cyclase, thereby increasing the concentration of cyclic AMP in the tissue, which, in turn, activates protein kinase to lead to the activation of hormone sensitive lipase.
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subjects Adenylyl Cyclases - metabolism
Adipose Tissue - metabolism
Animals
Cyclic AMP - metabolism
Enzyme Activation
Epididymis - metabolism
Fatty Acids, Nonesterified - blood
In Vitro Techniques
Lipase - metabolism
Lipid Metabolism
Male
Placental Lactogen - pharmacology
Protein Kinases - metabolism
Rats
title Lipolytic Action of Human Chorionic Somatomammotropin
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