Lipolytic Action of Human Chorionic Somatomammotropin
Human chorionic somatomammotropin extracted and purified from placenta at term was proved to have a lipolytic action in the epididymal fat pad of rats. The following mechanism appears to be involved in the lipolytic action of the hormone; human chorionic somatomammotropin activates adenyl cyclase, t...
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Veröffentlicht in: | Endocrinologia Japonica 1975, Vol.22(2), pp.123-129 |
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container_title | Endocrinologia Japonica |
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creator | MOCHIZUKI, MATSUTO MORIKAWA, HAJIME OHGA, YUZOH TOJO, SHIMPEI |
description | Human chorionic somatomammotropin extracted and purified from placenta at term was proved to have a lipolytic action in the epididymal fat pad of rats. The following mechanism appears to be involved in the lipolytic action of the hormone; human chorionic somatomammotropin activates adenyl cyclase, thereby increasing the concentration of cyclic AMP in the tissue, which, in turn, activates protein kinase to lead to the activation of hormone sensitive lipase. |
doi_str_mv | 10.1507/endocrj1954.22.123 |
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source | J-STAGE Free; MEDLINE; EZB-FREE-00999 freely available EZB journals |
subjects | Adenylyl Cyclases - metabolism Adipose Tissue - metabolism Animals Cyclic AMP - metabolism Enzyme Activation Epididymis - metabolism Fatty Acids, Nonesterified - blood In Vitro Techniques Lipase - metabolism Lipid Metabolism Male Placental Lactogen - pharmacology Protein Kinases - metabolism Rats |
title | Lipolytic Action of Human Chorionic Somatomammotropin |
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