Estradiol-dependent collagenolytic enzyme activity in long-term organ culture of human breast cancer

An organ culture method suitable for the maintenance of viable human breast cancer for at least 14 days has been described. This method was applied to a total of 94 breast cancer specimens. It allowed good survival of "soft" tumors of various histological types, with loose connective strom...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1975-08, Vol.35 (8), p.2039-2048
Hauptverfasser:	Heuson, J C, Pasteels, J L, Legros, N, Heuson-Stiennon, J, Leclercq, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma, Mucinous - metabolism Adenocarcinoma, Scirrhous - metabolism Adenocarcinoma, Scirrhous - pathology Adult Aged Breast Neoplasms - metabolism Breast Neoplasms - pathology Carcinoma - metabolism Carcinoma - pathology Carcinoma, Papillary - metabolism Estradiol - pharmacology Female Humans Hydrocortisone - pharmacology Insulin - pharmacology Male Microbial Collagenase - metabolism Middle Aged Organ Culture Techniques Prolactin - pharmacology Receptors, Drug Time Factors
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