Pre-operative neutralization of gastric acidity

The incidence of Mendelson's syndrome in the four major Auckland hospitals is reviewed. The frequency of this condition was reduced following the pre-operative administration of magnesium trisilicate mixture in two hospitals. A trial was conducted in a third hospital and this showed that a 52 p...

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Veröffentlicht in:Anaesthesia and intensive care 1975-08, Vol.3 (3), p.198-203
Hauptverfasser: Hutchinson, B R, Newson, A J
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creator Hutchinson, B R
Newson, A J
description The incidence of Mendelson's syndrome in the four major Auckland hospitals is reviewed. The frequency of this condition was reduced following the pre-operative administration of magnesium trisilicate mixture in two hospitals. A trial was conducted in a third hospital and this showed that a 52 per cent incidence of highly acid gastric juice (pH less than 2.5) in patients prepared for elective surgery was reduced by administration of magnesium trisilicate mixture at the time of premedication. When the magnesium trisilicate mixture was given within the 30 minutes prior to induction of anaesthesia, the number of patients with highly acid gastric content fell to one per cent.
doi_str_mv 10.1177/0310057X7500300304
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source MEDLINE; Alma/SFX Local Collection
subjects Administration, Oral
Adolescent
Adult
Aged
Antacids - administration & dosage
Child
Child, Preschool
Female
Gastric Acidity Determination
Gastric Juice - analysis
Humans
Magnesium - administration & dosage
Male
Middle Aged
Pneumonia, Aspiration - prevention & control
Preanesthetic Medication
Preoperative Care
Silicic Acid - administration & dosage
Silicon Dioxide - administration & dosage
Syndrome
title Pre-operative neutralization of gastric acidity
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