Pre-operative neutralization of gastric acidity
The incidence of Mendelson's syndrome in the four major Auckland hospitals is reviewed. The frequency of this condition was reduced following the pre-operative administration of magnesium trisilicate mixture in two hospitals. A trial was conducted in a third hospital and this showed that a 52 p...
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Veröffentlicht in: | Anaesthesia and intensive care 1975-08, Vol.3 (3), p.198-203 |
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description | The incidence of Mendelson's syndrome in the four major Auckland hospitals is reviewed. The frequency of this condition was reduced following the pre-operative administration of magnesium trisilicate mixture in two hospitals. A trial was conducted in a third hospital and this showed that a 52 per cent incidence of highly acid gastric juice (pH less than 2.5) in patients prepared for elective surgery was reduced by administration of magnesium trisilicate mixture at the time of premedication. When the magnesium trisilicate mixture was given within the 30 minutes prior to induction of anaesthesia, the number of patients with highly acid gastric content fell to one per cent. |
doi_str_mv | 10.1177/0310057X7500300304 |
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The frequency of this condition was reduced following the pre-operative administration of magnesium trisilicate mixture in two hospitals. A trial was conducted in a third hospital and this showed that a 52 per cent incidence of highly acid gastric juice (pH less than 2.5) in patients prepared for elective surgery was reduced by administration of magnesium trisilicate mixture at the time of premedication. When the magnesium trisilicate mixture was given within the 30 minutes prior to induction of anaesthesia, the number of patients with highly acid gastric content fell to one per cent.</description><identifier>ISSN: 0310-057X</identifier><identifier>EISSN: 1448-0271</identifier><identifier>DOI: 10.1177/0310057X7500300304</identifier><identifier>PMID: 170841</identifier><language>eng</language><publisher>United States</publisher><subject>Administration, Oral ; Adolescent ; Adult ; Aged ; Antacids - administration & dosage ; Child ; Child, Preschool ; Female ; Gastric Acidity Determination ; Gastric Juice - analysis ; Humans ; Magnesium - administration & dosage ; Male ; Middle Aged ; Pneumonia, Aspiration - prevention & control ; Preanesthetic Medication ; Preoperative Care ; Silicic Acid - administration & dosage ; Silicon Dioxide - administration & dosage ; Syndrome</subject><ispartof>Anaesthesia and intensive care, 1975-08, Vol.3 (3), p.198-203</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1884-b3d279cd0962b3ed70a366e8cc0bf0ec5d758e90db88cb22d81884ee3c288e3d3</citedby><cites>FETCH-LOGICAL-c1884-b3d279cd0962b3ed70a366e8cc0bf0ec5d758e90db88cb22d81884ee3c288e3d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/170841$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hutchinson, B R</creatorcontrib><creatorcontrib>Newson, A J</creatorcontrib><title>Pre-operative neutralization of gastric acidity</title><title>Anaesthesia and intensive care</title><addtitle>Anaesth Intensive Care</addtitle><description>The incidence of Mendelson's syndrome in the four major Auckland hospitals is reviewed. The frequency of this condition was reduced following the pre-operative administration of magnesium trisilicate mixture in two hospitals. A trial was conducted in a third hospital and this showed that a 52 per cent incidence of highly acid gastric juice (pH less than 2.5) in patients prepared for elective surgery was reduced by administration of magnesium trisilicate mixture at the time of premedication. When the magnesium trisilicate mixture was given within the 30 minutes prior to induction of anaesthesia, the number of patients with highly acid gastric content fell to one per cent.</description><subject>Administration, Oral</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Antacids - administration & dosage</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Gastric Acidity Determination</subject><subject>Gastric Juice - analysis</subject><subject>Humans</subject><subject>Magnesium - administration & dosage</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pneumonia, Aspiration - prevention & control</subject><subject>Preanesthetic Medication</subject><subject>Preoperative Care</subject><subject>Silicic Acid - administration & dosage</subject><subject>Silicon Dioxide - administration & dosage</subject><subject>Syndrome</subject><issn>0310-057X</issn><issn>1448-0271</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1975</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkEtLxDAUhYP4Gkf_gLjoyl2dm6RtbpcyjA8Y0IWCu5ImtxLpy6QVxl_v1BlwIVw4XPi-sziMXXK44VypBUgOkKo3lQLI6ZIDNuNJgjEIxQ_ZbALiiThlZyF8APBcqPSEHXMFmPAZWzx7iruevB7cF0UtjYPXtfvevl0bdVX0rsPgnYm0cdYNm3N2VOk60MU-5-z1bvWyfIjXT_ePy9t1bDhiEpfSCpUbC3kmSklWgZZZRmgMlBWQSa1KkXKwJaIphbA4aUTSCESSVs7Z9a63993nSGEoGhcM1bVuqRtDgSKXXAncgmIHGt-F4Kkqeu8a7TcFh2Iaqfg_0la62rePZUP2T_ldRf4AXvBhQw</recordid><startdate>197508</startdate><enddate>197508</enddate><creator>Hutchinson, B R</creator><creator>Newson, A J</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197508</creationdate><title>Pre-operative neutralization of gastric acidity</title><author>Hutchinson, B R ; Newson, A J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1884-b3d279cd0962b3ed70a366e8cc0bf0ec5d758e90db88cb22d81884ee3c288e3d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1975</creationdate><topic>Administration, Oral</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Antacids - administration & dosage</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Gastric Acidity Determination</topic><topic>Gastric Juice - analysis</topic><topic>Humans</topic><topic>Magnesium - administration & dosage</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pneumonia, Aspiration - prevention & control</topic><topic>Preanesthetic Medication</topic><topic>Preoperative Care</topic><topic>Silicic Acid - administration & dosage</topic><topic>Silicon Dioxide - administration & dosage</topic><topic>Syndrome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hutchinson, B R</creatorcontrib><creatorcontrib>Newson, A J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Anaesthesia and intensive care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hutchinson, B R</au><au>Newson, A J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pre-operative neutralization of gastric acidity</atitle><jtitle>Anaesthesia and intensive care</jtitle><addtitle>Anaesth Intensive Care</addtitle><date>1975-08</date><risdate>1975</risdate><volume>3</volume><issue>3</issue><spage>198</spage><epage>203</epage><pages>198-203</pages><issn>0310-057X</issn><eissn>1448-0271</eissn><abstract>The incidence of Mendelson's syndrome in the four major Auckland hospitals is reviewed. The frequency of this condition was reduced following the pre-operative administration of magnesium trisilicate mixture in two hospitals. A trial was conducted in a third hospital and this showed that a 52 per cent incidence of highly acid gastric juice (pH less than 2.5) in patients prepared for elective surgery was reduced by administration of magnesium trisilicate mixture at the time of premedication. When the magnesium trisilicate mixture was given within the 30 minutes prior to induction of anaesthesia, the number of patients with highly acid gastric content fell to one per cent.</abstract><cop>United States</cop><pmid>170841</pmid><doi>10.1177/0310057X7500300304</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Alma/SFX Local Collection |
subjects | Administration, Oral Adolescent Adult Aged Antacids - administration & dosage Child Child, Preschool Female Gastric Acidity Determination Gastric Juice - analysis Humans Magnesium - administration & dosage Male Middle Aged Pneumonia, Aspiration - prevention & control Preanesthetic Medication Preoperative Care Silicic Acid - administration & dosage Silicon Dioxide - administration & dosage Syndrome |
title | Pre-operative neutralization of gastric acidity |
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