Genetic Linkage between the HL-A System and a Deficit of the Second Component (C2) of Complement
From a family of 14 individuals, evidence was obtained suggesting linkage between the HL-A haplotypes and the transmission of a 50 percent deficit in the functional activity of the C2 component of complement.
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Veröffentlicht in: | Science (American Association for the Advancement of Science) 1975-06, Vol.188 (4192), p.1020-1022 |
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container_title | Science (American Association for the Advancement of Science) |
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creator | Wolski, Kenneth P. Schmid, Frank R. Mittal, Kamal K. |
description | From a family of 14 individuals, evidence was obtained suggesting linkage between the HL-A haplotypes and the transmission of a 50 percent deficit in the functional activity of the C2 component of complement. |
doi_str_mv | 10.1126/science.1145185 |
format | Article |
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language | eng |
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source | MEDLINE; American Association for the Advancement of Science; Jstor Complete Legacy |
subjects | Adolescent Adult Aged Alleles Amino acids Complement C2 - deficiency Complement System Proteins - deficiency Evolution Female Genetic inheritance Genetic Linkage Genetic mutation Haplotypes Heterozygote Histocompatibility Antigens HLA Antigens Homozygote Humans Male Middle Aged Molecules Pedigree Siblings Systemic lupus erythematosus |
title | Genetic Linkage between the HL-A System and a Deficit of the Second Component (C2) of Complement |
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