Histology of Induced Bovine Lactogenesis
Nine cycling nonlactating dairy cows were treated hormonally to induce lactation with progesterone, estradiol-17β, and dexamethasone. Mammary tissue biopsies were taken on days 18, 21, and 23 after initiation of treatment (different three cows for each period). First milking was initiated on day 21...
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| Veröffentlicht in: | Journal of dairy science 1975-06, Vol.58 (6), p.853-860 |
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| container_title | Journal of dairy science |
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| creator | Howe, J.E. Heald, C.W. Bibb, T.L. |
| description | Nine cycling nonlactating dairy cows were treated hormonally to induce lactation with progesterone, estradiol-17β, and dexamethasone. Mammary tissue biopsies were taken on days 18, 21, and 23 after initiation of treatment (different three cows for each period). First milking was initiated on day 21 in the latter two groups. Mean differences in tissue development (percent area) between day 18 and 23 were, epithelium + 11.1%, stroma−25.9%, alveolar lumen + 13.9%, adipose + 1.58%, duct−.74%, and + 15 nuclei/alveolar section. On day 18 epithelia containing small lipid droplets predominated but were replaced with mixed lipid droplets by day 23. Epithelia day 18 had elongated dark staining nuclei. Epithelia on day 23 had spherically shaped nuclei often containing several nucleoli and an increased cytoplasmic/nuclear ratio. Marked histological development occurred from 18 to 23 days after initiation of treatment. Mammary tissue development in nongravid hormonally treated animals was equal to or greater than 2-wk-prepartum tissue but less than 2-day-prepartum tissue for natural lactations. |
| doi_str_mv | 10.3168/jds.S0022-0302(75)84649-2 |
| format | Article |
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Mammary tissue biopsies were taken on days 18, 21, and 23 after initiation of treatment (different three cows for each period). First milking was initiated on day 21 in the latter two groups. Mean differences in tissue development (percent area) between day 18 and 23 were, epithelium + 11.1%, stroma−25.9%, alveolar lumen + 13.9%, adipose + 1.58%, duct−.74%, and + 15 nuclei/alveolar section. On day 18 epithelia containing small lipid droplets predominated but were replaced with mixed lipid droplets by day 23. Epithelia day 18 had elongated dark staining nuclei. Epithelia on day 23 had spherically shaped nuclei often containing several nucleoli and an increased cytoplasmic/nuclear ratio. Marked histological development occurred from 18 to 23 days after initiation of treatment. Mammary tissue development in nongravid hormonally treated animals was equal to or greater than 2-wk-prepartum tissue but less than 2-day-prepartum tissue for natural lactations.</description><identifier>ISSN: 0022-0302</identifier><identifier>EISSN: 1525-3198</identifier><identifier>DOI: 10.3168/jds.S0022-0302(75)84649-2</identifier><identifier>PMID: 1170220</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adipose Tissue - drug effects ; Animals ; Biopsy ; Cattle ; Cell Nucleus - drug effects ; Dexamethasone - pharmacology ; Epithelium - drug effects ; Estradiol - pharmacology ; Female ; Lactation - drug effects ; Mammary Glands, Animal - anatomy & histology ; Mammary Glands, Animal - drug effects ; Mammary Glands, Animal - ultrastructure ; Pregnancy ; Progesterone - pharmacology ; Time Factors</subject><ispartof>Journal of dairy science, 1975-06, Vol.58 (6), p.853-860</ispartof><rights>1975 American Dairy Science Association</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c481t-59c45802854333282d1ebcdfede6667978894072f24d912b0f6c8b163966ef7f3</citedby><cites>FETCH-LOGICAL-c481t-59c45802854333282d1ebcdfede6667978894072f24d912b0f6c8b163966ef7f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.3168/jds.S0022-0302(75)84649-2$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3548,27867,27922,27923,45993</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1170220$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Howe, J.E.</creatorcontrib><creatorcontrib>Heald, C.W.</creatorcontrib><creatorcontrib>Bibb, T.L.</creatorcontrib><title>Histology of Induced Bovine Lactogenesis</title><title>Journal of dairy science</title><addtitle>J Dairy Sci</addtitle><description>Nine cycling nonlactating dairy cows were treated hormonally to induce lactation with progesterone, estradiol-17β, and dexamethasone. Mammary tissue biopsies were taken on days 18, 21, and 23 after initiation of treatment (different three cows for each period). First milking was initiated on day 21 in the latter two groups. Mean differences in tissue development (percent area) between day 18 and 23 were, epithelium + 11.1%, stroma−25.9%, alveolar lumen + 13.9%, adipose + 1.58%, duct−.74%, and + 15 nuclei/alveolar section. On day 18 epithelia containing small lipid droplets predominated but were replaced with mixed lipid droplets by day 23. Epithelia day 18 had elongated dark staining nuclei. Epithelia on day 23 had spherically shaped nuclei often containing several nucleoli and an increased cytoplasmic/nuclear ratio. Marked histological development occurred from 18 to 23 days after initiation of treatment. Mammary tissue development in nongravid hormonally treated animals was equal to or greater than 2-wk-prepartum tissue but less than 2-day-prepartum tissue for natural lactations.</description><subject>Adipose Tissue - drug effects</subject><subject>Animals</subject><subject>Biopsy</subject><subject>Cattle</subject><subject>Cell Nucleus - drug effects</subject><subject>Dexamethasone - pharmacology</subject><subject>Epithelium - drug effects</subject><subject>Estradiol - pharmacology</subject><subject>Female</subject><subject>Lactation - drug effects</subject><subject>Mammary Glands, Animal - anatomy & histology</subject><subject>Mammary Glands, Animal - drug effects</subject><subject>Mammary Glands, Animal - ultrastructure</subject><subject>Pregnancy</subject><subject>Progesterone - pharmacology</subject><subject>Time Factors</subject><issn>0022-0302</issn><issn>1525-3198</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1975</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>K30</sourceid><recordid>eNqNkE1rFEEQhhsxxDX6E4QVMSSHif091Udd1AQWPKjnYra7ZtPL7HScnonk36c3ExRyyqkp3uetLh7G3gt-oYSFT7uQL35yLmXFFZdntTkHbbWr5Au2EEaaSgkHL9niH_KKvc55V0YhuTlmx0LUJeILdnYZ85i6tL1bpnZ51YfJU1h-Sbexp-W68WPaUk855jfsqG26TG8f3xP2-9vXX6vLav3j-9Xq87ryGsRYGee1AS7BaKWUBBkEbXxoKZC1tnY1gNO8lq3UwQm54a31sBFWOWuprVt1wk7nvTdD-jNRHnEfs6eua3pKU0aQ4GrHXQE_PAF3aRr6chsKUA4s16AL5WbKDynngVq8GeK-Ge5QcDy4xOISH1ziQRTWBh9coizdd48_TJs9hf_NWV7JP875ddxe_40DYd43XVdocdhqAC2CUYVbzRwVb7eRBsw-Ul9El44fMaT4jGvuAUu5kGE</recordid><startdate>197506</startdate><enddate>197506</enddate><creator>Howe, J.E.</creator><creator>Heald, C.W.</creator><creator>Bibb, T.L.</creator><general>Elsevier Inc</general><general>Am Dairy Sci Assoc</general><general>American Dairy Science Association</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7WH</scope><scope>K30</scope><scope>PAAUG</scope><scope>PAWHS</scope><scope>PAWZZ</scope><scope>PAXOH</scope><scope>PBHAV</scope><scope>PBQSW</scope><scope>PBYQZ</scope><scope>PCIWU</scope><scope>PCMID</scope><scope>PCZJX</scope><scope>PDGRG</scope><scope>PDWWI</scope><scope>PETMR</scope><scope>PFVGT</scope><scope>PGXDX</scope><scope>PIHIL</scope><scope>PISVA</scope><scope>PJCTQ</scope><scope>PJTMS</scope><scope>PLCHJ</scope><scope>PMHAD</scope><scope>PNQDJ</scope><scope>POUND</scope><scope>PPLAD</scope><scope>PQAPC</scope><scope>PQCAN</scope><scope>PQCMW</scope><scope>PQEME</scope><scope>PQHKH</scope><scope>PQMID</scope><scope>PQNCT</scope><scope>PQNET</scope><scope>PQSCT</scope><scope>PQSET</scope><scope>PSVJG</scope><scope>PVMQY</scope><scope>PZGFC</scope><scope>7X8</scope></search><sort><creationdate>197506</creationdate><title>Histology of Induced Bovine Lactogenesis</title><author>Howe, J.E. ; Heald, C.W. ; Bibb, T.L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c481t-59c45802854333282d1ebcdfede6667978894072f24d912b0f6c8b163966ef7f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1975</creationdate><topic>Adipose Tissue - 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Mammary tissue biopsies were taken on days 18, 21, and 23 after initiation of treatment (different three cows for each period). First milking was initiated on day 21 in the latter two groups. Mean differences in tissue development (percent area) between day 18 and 23 were, epithelium + 11.1%, stroma−25.9%, alveolar lumen + 13.9%, adipose + 1.58%, duct−.74%, and + 15 nuclei/alveolar section. On day 18 epithelia containing small lipid droplets predominated but were replaced with mixed lipid droplets by day 23. Epithelia day 18 had elongated dark staining nuclei. Epithelia on day 23 had spherically shaped nuclei often containing several nucleoli and an increased cytoplasmic/nuclear ratio. Marked histological development occurred from 18 to 23 days after initiation of treatment. 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| ispartof | Journal of dairy science, 1975-06, Vol.58 (6), p.853-860 |
| issn | 0022-0302 1525-3198 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete; Periodicals Index Online; EZB-FREE-00999 freely available EZB journals |
| subjects | Adipose Tissue - drug effects Animals Biopsy Cattle Cell Nucleus - drug effects Dexamethasone - pharmacology Epithelium - drug effects Estradiol - pharmacology Female Lactation - drug effects Mammary Glands, Animal - anatomy & histology Mammary Glands, Animal - drug effects Mammary Glands, Animal - ultrastructure Pregnancy Progesterone - pharmacology Time Factors |
| title | Histology of Induced Bovine Lactogenesis |
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