Elevation of a serum component in periodontal disease capable of modulating chemotactic infiltration
Serum from dental patients was examined for its capacity to affect migration of polymorphonuclear leukocytes toward a complement‐independent chemotactic factor, bacterial filtrate of Escherichia coli, (BF), Seven subjects with advanced periodontitis, documented with clinical measurements of pocket d...
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Veröffentlicht in: | Journal of periodontal research 1975-04, Vol.10 (2), p.65-72 |
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container_title | Journal of periodontal research |
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creator | Gothier, Douglas E. Richard Gaumer, H. Pihlstrom, Bruce L. Folke, Lars E. A. |
description | Serum from dental patients was examined for its capacity to affect migration of polymorphonuclear leukocytes toward a complement‐independent chemotactic factor, bacterial filtrate of Escherichia coli, (BF), Seven subjects with advanced periodontitis, documented with clinical measurements of pocket depth, loss of attachment, indices for gingival inflammation and oral hygiene, were paired with normal subjects of similar age and sex.
This study shows that patients whose only apparent clinical symptom was severe periodontal inflammation harbor a heat‐stable, serum component which neutralizes factors chemotactic for polymorphonuclear leukocytes. A role for this component in modulation of inflammatory infiltration is discussed. |
doi_str_mv | 10.1111/j.1600-0765.1975.tb00009.x |
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This study shows that patients whose only apparent clinical symptom was severe periodontal inflammation harbor a heat‐stable, serum component which neutralizes factors chemotactic for polymorphonuclear leukocytes. A role for this component in modulation of inflammatory infiltration is discussed.</description><subject>Chemotaxis</subject><subject>Dentistry</subject><subject>Escherichia coli - immunology</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Periodontitis - blood</subject><subject>Periodontitis - immunology</subject><issn>0022-3484</issn><issn>1600-0765</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1975</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkM1u1DAUhS3E31B4AxYWC3YJdhLbMRILqIa2qAKE-JHYWI59Ax6cONgJTN--TmdU1tyNF_d8x7ofQs8oKWmeF7uSckIKIjgrqRSsnDuSR5b7O2hzu7qLNoRUVVE3bfMQPUpplzMVF_IBuk-rpq7bDbJbD3_07MKIQ481ThCXAZswTGGEccZuxBNEF2wYZ-2xdQl0Amz0pDsPKzMEu_jcMP7A5icMYdZmdiaDvfNzvKl-jO712id4cnxP0Je328-n58Xlh7OL09eXhWkIYwVQKXln-kr3NRe2sS0BIURHpSa6Zl0jSW8tWJaPkz2TrKPGNrw11OQga-oT9PzQO8Xwe4E0q8ElA97rEcKSVFu1bSMIz8GXh6CJIaUIvZqiG3S8UpSo1bDaqVWjWjWq1bA6Glb7DD89_rJ0A9h_6I3SvH51WP91Hq7-o1i9-7TlLPPFgXdphv0tr-MvxUWdgW_vzxR_8_V7K84_KlFfA-75m_Y</recordid><startdate>197504</startdate><enddate>197504</enddate><creator>Gothier, Douglas E.</creator><creator>Richard Gaumer, H.</creator><creator>Pihlstrom, Bruce L.</creator><creator>Folke, Lars E. A.</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197504</creationdate><title>Elevation of a serum component in periodontal disease capable of modulating chemotactic infiltration</title><author>Gothier, Douglas E. ; Richard Gaumer, H. ; Pihlstrom, Bruce L. ; Folke, Lars E. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4055-e1996bcf2af367d4d80e777b19a0a35b490fdded50769f595b1cd468c1c0e7543</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1975</creationdate><topic>Chemotaxis</topic><topic>Dentistry</topic><topic>Escherichia coli - immunology</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Periodontitis - blood</topic><topic>Periodontitis - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gothier, Douglas E.</creatorcontrib><creatorcontrib>Richard Gaumer, H.</creatorcontrib><creatorcontrib>Pihlstrom, Bruce L.</creatorcontrib><creatorcontrib>Folke, Lars E. A.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of periodontal research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gothier, Douglas E.</au><au>Richard Gaumer, H.</au><au>Pihlstrom, Bruce L.</au><au>Folke, Lars E. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Elevation of a serum component in periodontal disease capable of modulating chemotactic infiltration</atitle><jtitle>Journal of periodontal research</jtitle><addtitle>J Periodontal Res</addtitle><date>1975-04</date><risdate>1975</risdate><volume>10</volume><issue>2</issue><spage>65</spage><epage>72</epage><pages>65-72</pages><issn>0022-3484</issn><eissn>1600-0765</eissn><abstract>Serum from dental patients was examined for its capacity to affect migration of polymorphonuclear leukocytes toward a complement‐independent chemotactic factor, bacterial filtrate of Escherichia coli, (BF), Seven subjects with advanced periodontitis, documented with clinical measurements of pocket depth, loss of attachment, indices for gingival inflammation and oral hygiene, were paired with normal subjects of similar age and sex.
This study shows that patients whose only apparent clinical symptom was severe periodontal inflammation harbor a heat‐stable, serum component which neutralizes factors chemotactic for polymorphonuclear leukocytes. A role for this component in modulation of inflammatory infiltration is discussed.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>124338</pmid><doi>10.1111/j.1600-0765.1975.tb00009.x</doi><tpages>8</tpages></addata></record> |
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source | Wiley-Blackwell Journals; MEDLINE |
subjects | Chemotaxis Dentistry Escherichia coli - immunology Female Humans Male Periodontitis - blood Periodontitis - immunology |
title | Elevation of a serum component in periodontal disease capable of modulating chemotactic infiltration |
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