Kinase and deaminase activity in a variety of subcutaneous mouse tumors

Extracts of solid mouse tumors were examined for deoxycytidine kinase and deaminase activities. 1beta-D-Arabinofuranosylcytosine nucleotide was formed at a rate of 45 nmoles/hr by Glioma 26/57 and only 14 nmoles/hr by Ridgway osteogenic sarcoma. Deaminase activity was highest in Lewis lung (114 nmol...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1975-07, Vol.35 (7), p.1799-1803
Hauptverfasser:	Furner, R L, Mellett, L B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - enzymology Aminohydrolases - metabolism Animals Cell Line Chick Embryo Cytarabine - biosynthesis Freezing Glioma - enzymology Lung Neoplasms - enzymology Mammary Neoplasms, Experimental - enzymology Melanoma - enzymology Mice Mice, Inbred AKR Mice, Inbred C3H Mice, Inbred C57BL Mice, Inbred DBA Neoplasms, Experimental - enzymology Osteosarcoma - enzymology Phosphotransferases - metabolism Pyrimidine Nucleotides - metabolism Sarcoma 180 - enzymology Tetrahydrouridine - pharmacology Uridine
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