Uterotrophic Action of the Insecticide Methoxychlor
Dusting of rats and mice, as well as oral treatment with the insecticide methoxychlor, produced uterine weight increase in these rodents. Ablation of the ovaries, adrenals, or pituitary did not alter this effect, thus indicating a direct trophic action of this agent on the uterus. It is apparent tha...
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| Veröffentlicht in: | Science (American Association for the Advancement of Science) 1961-03, Vol.133 (3453), p.647-648 |
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| container_title | Science (American Association for the Advancement of Science) |
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| creator | Tullner, William W. |
| description | Dusting of rats and mice, as well as oral treatment with the insecticide methoxychlor, produced uterine weight increase in these rodents. Ablation of the ovaries, adrenals, or pituitary did not alter this effect, thus indicating a direct trophic action of this agent on the uterus. It is apparent that the application of this insecticide to animals used for hormonal experiments introduces an additional variable. |
| doi_str_mv | 10.1126/science.133.3453.647 |
| format | Article |
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Ablation of the ovaries, adrenals, or pituitary did not alter this effect, thus indicating a direct trophic action of this agent on the uterus. It is apparent that the application of this insecticide to animals used for hormonal experiments introduces an additional variable.</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.133.3453.647</identifier><identifier>PMID: 13778585</identifier><language>eng</language><publisher>United States: American Association for the Advancement of Science</publisher><subject>Animals ; DDT - analogs & derivatives ; Female ; Humans ; Insecticides ; Isomers ; Methoxychlor ; Mice ; Old Medline ; Ovaries ; Parabiosis ; Pituitary Gland ; Rats ; Sesame oil ; Uterus ; Uterus - pharmacology</subject><ispartof>Science (American Association for the Advancement of Science), 1961-03, Vol.133 (3453), p.647-648</ispartof><rights>Copyright 1961 American Association for the Advancement of Science</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c354t-e7e83df7fd4f1e7e8c8c0cf95f880081a07a8ecf9e87d0b6a9b6d66759a50ee43</citedby><cites>FETCH-LOGICAL-c354t-e7e83df7fd4f1e7e8c8c0cf95f880081a07a8ecf9e87d0b6a9b6d66759a50ee43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/1706609$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/1706609$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,776,780,799,2871,2872,27901,27902,57992,58225</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13778585$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tullner, William W.</creatorcontrib><title>Uterotrophic Action of the Insecticide Methoxychlor</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>Dusting of rats and mice, as well as oral treatment with the insecticide methoxychlor, produced uterine weight increase in these rodents. Ablation of the ovaries, adrenals, or pituitary did not alter this effect, thus indicating a direct trophic action of this agent on the uterus. It is apparent that the application of this insecticide to animals used for hormonal experiments introduces an additional variable.</description><subject>Animals</subject><subject>DDT - analogs & derivatives</subject><subject>Female</subject><subject>Humans</subject><subject>Insecticides</subject><subject>Isomers</subject><subject>Methoxychlor</subject><subject>Mice</subject><subject>Old Medline</subject><subject>Ovaries</subject><subject>Parabiosis</subject><subject>Pituitary Gland</subject><subject>Rats</subject><subject>Sesame oil</subject><subject>Uterus</subject><subject>Uterus - pharmacology</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1961</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMtqAjEUhkNpqdb2DaTMqruZnpjJZZYivQiWbuo6jJkTZmSc2CRCfftGFFwdzn9bfIRMKRSUzsRrMB0OBgvKWMFKzgpRyhsyplDxvJoBuyVjACZyBZKPyEMIW4DkVeyejCiTUnHFx4StI3oXvdu3ncnmJnZuyJzNYovZcgiYBNM1mH1hbN3f0bS984_kztZ9wKfLnZD1-9vP4jNffX8sF_NVbhgvY44SFWustE1p6ekxyoCxFbdKAShag6wVJgGVbGAj6mojGiEkr2oOiCWbkJfz7t673wOGqHddMNj39YDuELSaKQZcQgqW56DxLgSPVu99t6v9UVPQJ1j6AksnWPoESydYqfZ82T9sdthcSxc6KTA9B7YhOn_1JQgBFfsHV0BxPA</recordid><startdate>19610303</startdate><enddate>19610303</enddate><creator>Tullner, William W.</creator><general>American Association for the Advancement of Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19610303</creationdate><title>Uterotrophic Action of the Insecticide Methoxychlor</title><author>Tullner, William W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c354t-e7e83df7fd4f1e7e8c8c0cf95f880081a07a8ecf9e87d0b6a9b6d66759a50ee43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1961</creationdate><topic>Animals</topic><topic>DDT - analogs & derivatives</topic><topic>Female</topic><topic>Humans</topic><topic>Insecticides</topic><topic>Isomers</topic><topic>Methoxychlor</topic><topic>Mice</topic><topic>Old Medline</topic><topic>Ovaries</topic><topic>Parabiosis</topic><topic>Pituitary Gland</topic><topic>Rats</topic><topic>Sesame oil</topic><topic>Uterus</topic><topic>Uterus - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tullner, William W.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tullner, William W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Uterotrophic Action of the Insecticide Methoxychlor</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1961-03-03</date><risdate>1961</risdate><volume>133</volume><issue>3453</issue><spage>647</spage><epage>648</epage><pages>647-648</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><abstract>Dusting of rats and mice, as well as oral treatment with the insecticide methoxychlor, produced uterine weight increase in these rodents. Ablation of the ovaries, adrenals, or pituitary did not alter this effect, thus indicating a direct trophic action of this agent on the uterus. It is apparent that the application of this insecticide to animals used for hormonal experiments introduces an additional variable.</abstract><cop>United States</cop><pub>American Association for the Advancement of Science</pub><pmid>13778585</pmid><doi>10.1126/science.133.3453.647</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-8075 |
| ispartof | Science (American Association for the Advancement of Science), 1961-03, Vol.133 (3453), p.647-648 |
| issn | 0036-8075 1095-9203 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_82830570 |
| source | Jstor Complete Legacy; MEDLINE; Science Magazine |
| subjects | Animals DDT - analogs & derivatives Female Humans Insecticides Isomers Methoxychlor Mice Old Medline Ovaries Parabiosis Pituitary Gland Rats Sesame oil Uterus Uterus - pharmacology |
| title | Uterotrophic Action of the Insecticide Methoxychlor |
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