Biologically Active Peptides in Physalia Toxin.
Summary and conclusions The crude toxin of Physalia nematocysts withstands lyophilization without significant loss of toxicity. Physalia toxin may be separated into component peptides by one-dimensional chromatography in 80% aqueous n-propanol. Each of the resultant peptides retains considerable tox...
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Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1961-07, Vol.107 (3), p.670-672 |
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container_title | Experimental biology and medicine (Maywood, N.J.) |
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creator | Lane, Charles E. Coursen, Bradner W. Hines, Kenneth |
description | Summary and conclusions
The crude toxin of Physalia nematocysts withstands lyophilization without significant loss of toxicity. Physalia toxin may be separated into component peptides by one-dimensional chromatography in 80% aqueous n-propanol. Each of the resultant peptides retains considerable toxicity for the fiddler crab, Uca pugilator. Crude toxin of Physalia nematocysts has no effect on growth of marine yeasts or marine bacteria. Toxin preparations have been shown to be without significant effect on growth or reproduction of the ciliate protozoans, Paramecium caudatum and Tetrahymena gellii. |
doi_str_mv | 10.3181/00379727-107-26723 |
format | Article |
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The crude toxin of Physalia nematocysts withstands lyophilization without significant loss of toxicity. Physalia toxin may be separated into component peptides by one-dimensional chromatography in 80% aqueous n-propanol. Each of the resultant peptides retains considerable toxicity for the fiddler crab, Uca pugilator. Crude toxin of Physalia nematocysts has no effect on growth of marine yeasts or marine bacteria. Toxin preparations have been shown to be without significant effect on growth or reproduction of the ciliate protozoans, Paramecium caudatum and Tetrahymena gellii.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-107-26723</identifier><identifier>PMID: 13758710</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Animals ; Antitoxins - chemistry ; Cnidaria - chemistry ; Hydrozoa ; Old Medline ; Peptides - chemistry ; Toxins, Biological - chemistry</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1961-07, Vol.107 (3), p.670-672</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c341t-32cfbb267408382d11c41653cd0ea4dc9ae8053b9df90ca1798fc8ceb178a2a73</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13758710$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lane, Charles E.</creatorcontrib><creatorcontrib>Coursen, Bradner W.</creatorcontrib><creatorcontrib>Hines, Kenneth</creatorcontrib><title>Biologically Active Peptides in Physalia Toxin.</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary and conclusions
The crude toxin of Physalia nematocysts withstands lyophilization without significant loss of toxicity. Physalia toxin may be separated into component peptides by one-dimensional chromatography in 80% aqueous n-propanol. Each of the resultant peptides retains considerable toxicity for the fiddler crab, Uca pugilator. Crude toxin of Physalia nematocysts has no effect on growth of marine yeasts or marine bacteria. Toxin preparations have been shown to be without significant effect on growth or reproduction of the ciliate protozoans, Paramecium caudatum and Tetrahymena gellii.</description><subject>Animals</subject><subject>Antitoxins - chemistry</subject><subject>Cnidaria - chemistry</subject><subject>Hydrozoa</subject><subject>Old Medline</subject><subject>Peptides - chemistry</subject><subject>Toxins, Biological - chemistry</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1961</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD1PwzAQhi0EoqXwBxhQJja3PjuJ7bFU5UOqRIcyW47jFFduXOIE0X9PSovYmE46Pe-ruwehWyBjBgImhDAuOeUYCMc055SdoSFkLMMsl_IcDQ8APhADdBXjhhDIOM0v0QAYzwQHMkSTBxd8WDujvd8nU9O6T5ss7a51pY2Jq5Pl-z5q73SyCl-uHl-ji0r7aG9Oc4TeHuer2TNevD69zKYLbFgKLWbUVEXR35QSwQQtAUwKecZMSaxOSyO1FSRjhSwrSYwGLkVlhLEFcKGp5myE7o-9uyZ8dDa2auuisd7r2oYuKkEFSVOa9SA9gqYJMTa2UrvGbXWzV0DUQZP61dQvuPrR1IfuTu1dsbXlX-TkpQcmRyDqtVWb0DV1_-1_ld8eX28L</recordid><startdate>196107</startdate><enddate>196107</enddate><creator>Lane, Charles E.</creator><creator>Coursen, Bradner W.</creator><creator>Hines, Kenneth</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196107</creationdate><title>Biologically Active Peptides in Physalia Toxin.</title><author>Lane, Charles E. ; Coursen, Bradner W. ; Hines, Kenneth</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c341t-32cfbb267408382d11c41653cd0ea4dc9ae8053b9df90ca1798fc8ceb178a2a73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1961</creationdate><topic>Animals</topic><topic>Antitoxins - chemistry</topic><topic>Cnidaria - chemistry</topic><topic>Hydrozoa</topic><topic>Old Medline</topic><topic>Peptides - chemistry</topic><topic>Toxins, Biological - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lane, Charles E.</creatorcontrib><creatorcontrib>Coursen, Bradner W.</creatorcontrib><creatorcontrib>Hines, Kenneth</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lane, Charles E.</au><au>Coursen, Bradner W.</au><au>Hines, Kenneth</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Biologically Active Peptides in Physalia Toxin.</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1961-07</date><risdate>1961</risdate><volume>107</volume><issue>3</issue><spage>670</spage><epage>672</epage><pages>670-672</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary and conclusions
The crude toxin of Physalia nematocysts withstands lyophilization without significant loss of toxicity. Physalia toxin may be separated into component peptides by one-dimensional chromatography in 80% aqueous n-propanol. Each of the resultant peptides retains considerable toxicity for the fiddler crab, Uca pugilator. Crude toxin of Physalia nematocysts has no effect on growth of marine yeasts or marine bacteria. Toxin preparations have been shown to be without significant effect on growth or reproduction of the ciliate protozoans, Paramecium caudatum and Tetrahymena gellii.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>13758710</pmid><doi>10.3181/00379727-107-26723</doi><tpages>3</tpages></addata></record> |
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subjects | Animals Antitoxins - chemistry Cnidaria - chemistry Hydrozoa Old Medline Peptides - chemistry Toxins, Biological - chemistry |
title | Biologically Active Peptides in Physalia Toxin. |
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