Isolation and identification of 1,25-dihydroxyvitamin D2

The chemical synthesis of [3alpha-3H]vitamin D2 of high specific activity has been described. With the use of this radioactive material, the existence of a polar metabolite believed to be the active form of vitamin D2 in the rat and chick has been demonstrated. It has been isolated in pure form from...

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Veröffentlicht in:	Biochemistry (Easton) 1975-03, Vol.14 (6), p.1250-1256
Hauptverfasser:	Jones, Glenville, Schnoes, Heinrich K, DeLuca, Hector F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chickens Dihydroxycholecalciferols - therapeutic use Ergocalciferols - analogs & derivatives Ergocalciferols - isolation & purification Ergocalciferols - physiology Hydroxysteroids - physiology Kidney - metabolism Male Mitochondria - metabolism Rats Rickets - drug therapy Rickets - metabolism
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