Effects of protamine and acridine orange on the muscular activity of the guinea-pig's uterus
Studying the exciting effects of protamine and acridine orange on the guinea-pig's uterus it was demonstrated that both substances accumulated within the nucleus of the muscle cell. Other basic substances, such as naphthylamines and benzidine, which, though penetrating into the cells, did not a...
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| Veröffentlicht in: | Experimental cell research 1961-02, Vol.23 (1), p.1-8 |
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| container_title | Experimental cell research |
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| creator | Klingenberg, H.G. Lipp, W. Müller, F. |
| description | Studying the exciting effects of protamine and acridine orange on the guinea-pig's uterus it was demonstrated that both substances accumulated within the nucleus of the muscle cell.
Other basic substances, such as naphthylamines and benzidine, which, though penetrating into the cells, did not accumulate within the nucleus, did not activate the smooth muscle.
The cell respiration was not altered by the basic substances.
The results are discussed with regard to the role of the cell nucleus in the autorhythmical activity of the smooth muscle. |
| doi_str_mv | 10.1016/0014-4827(61)90057-X |
| format | Article |
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Other basic substances, such as naphthylamines and benzidine, which, though penetrating into the cells, did not accumulate within the nucleus, did not activate the smooth muscle.
The cell respiration was not altered by the basic substances.
The results are discussed with regard to the role of the cell nucleus in the autorhythmical activity of the smooth muscle.</description><identifier>ISSN: 0014-4827</identifier><identifier>EISSN: 1090-2422</identifier><identifier>DOI: 10.1016/0014-4827(61)90057-X</identifier><identifier>PMID: 13756878</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Acridine Orange ; Acridines - pharmacology ; Female ; Guinea Pigs ; Humans ; Old Medline ; Protamines - pharmacology ; Uterus - pharmacology</subject><ispartof>Experimental cell research, 1961-02, Vol.23 (1), p.1-8</ispartof><rights>1961</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c360t-eb93a35dca31fdcbf322713cdcd06670815b414eae0e87dcd4be344f2ca11f0f3</citedby><cites>FETCH-LOGICAL-c360t-eb93a35dca31fdcbf322713cdcd06670815b414eae0e87dcd4be344f2ca11f0f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0014-4827(61)90057-X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13756878$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Klingenberg, H.G.</creatorcontrib><creatorcontrib>Lipp, W.</creatorcontrib><creatorcontrib>Müller, F.</creatorcontrib><title>Effects of protamine and acridine orange on the muscular activity of the guinea-pig's uterus</title><title>Experimental cell research</title><addtitle>Exp Cell Res</addtitle><description>Studying the exciting effects of protamine and acridine orange on the guinea-pig's uterus it was demonstrated that both substances accumulated within the nucleus of the muscle cell.
Other basic substances, such as naphthylamines and benzidine, which, though penetrating into the cells, did not accumulate within the nucleus, did not activate the smooth muscle.
The cell respiration was not altered by the basic substances.
The results are discussed with regard to the role of the cell nucleus in the autorhythmical activity of the smooth muscle.</description><subject>Acridine Orange</subject><subject>Acridines - pharmacology</subject><subject>Female</subject><subject>Guinea Pigs</subject><subject>Humans</subject><subject>Old Medline</subject><subject>Protamines - pharmacology</subject><subject>Uterus - pharmacology</subject><issn>0014-4827</issn><issn>1090-2422</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1961</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLAzEQx4Motj6-gciefBxWJ5vsoxdBSn1AwYtCD0LIJpMa2UdNdgv99mZt0ZunIZnff4b5EXJG4YYCzW4BKI95keRXGb2eAKR5vNgjYwoTiBOeJPtk_IuMyJH3nwBQFDQ7JCPK8jQr8mJM3mfGoOp81Jpo5dpO1rbBSDY6kspZPTxaJ5tlKE3UfWBU9171lXSh39m17TZDcmgs-wDLeGWXlz7qO3S9PyEHRlYeT3f1mLw9zF6nT_H85fF5ej-PFcugi7GcMMlSrSSjRqvSsCTJKVNaaciyHAqalpxylAhY5OGXl8g4N4mSlBow7JhcbOeGC7569J2orVdYVbLBtvciGJiEkUUA-RZUrvXeoRErZ2vpNoKCGKyKQZkYlImMih-rYhFi57v5fVmj_gvtNAbgbgtguHJt0QmvLDYKtXXBrtCt_X_DNyn4iBg</recordid><startdate>196102</startdate><enddate>196102</enddate><creator>Klingenberg, H.G.</creator><creator>Lipp, W.</creator><creator>Müller, F.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196102</creationdate><title>Effects of protamine and acridine orange on the muscular activity of the guinea-pig's uterus</title><author>Klingenberg, H.G. ; Lipp, W. ; Müller, F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-eb93a35dca31fdcbf322713cdcd06670815b414eae0e87dcd4be344f2ca11f0f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1961</creationdate><topic>Acridine Orange</topic><topic>Acridines - pharmacology</topic><topic>Female</topic><topic>Guinea Pigs</topic><topic>Humans</topic><topic>Old Medline</topic><topic>Protamines - pharmacology</topic><topic>Uterus - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Klingenberg, H.G.</creatorcontrib><creatorcontrib>Lipp, W.</creatorcontrib><creatorcontrib>Müller, F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental cell research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Klingenberg, H.G.</au><au>Lipp, W.</au><au>Müller, F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of protamine and acridine orange on the muscular activity of the guinea-pig's uterus</atitle><jtitle>Experimental cell research</jtitle><addtitle>Exp Cell Res</addtitle><date>1961-02</date><risdate>1961</risdate><volume>23</volume><issue>1</issue><spage>1</spage><epage>8</epage><pages>1-8</pages><issn>0014-4827</issn><eissn>1090-2422</eissn><abstract>Studying the exciting effects of protamine and acridine orange on the guinea-pig's uterus it was demonstrated that both substances accumulated within the nucleus of the muscle cell.
Other basic substances, such as naphthylamines and benzidine, which, though penetrating into the cells, did not accumulate within the nucleus, did not activate the smooth muscle.
The cell respiration was not altered by the basic substances.
The results are discussed with regard to the role of the cell nucleus in the autorhythmical activity of the smooth muscle.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>13756878</pmid><doi>10.1016/0014-4827(61)90057-X</doi><tpages>8</tpages></addata></record> |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Acridine Orange Acridines - pharmacology Female Guinea Pigs Humans Old Medline Protamines - pharmacology Uterus - pharmacology |
| title | Effects of protamine and acridine orange on the muscular activity of the guinea-pig's uterus |
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