Cross–Protection Between Venezuelan Equine Encephalomyelitis and Eastern Equine Encephalomyelitis Virus
Summary Mice were capable of with standing a large challenge dose of virulent Venezuelan equine encephalomyelitis virus and a substantial challenge dose of eastern equine encephalomyelitis virus after immunization with an attenuated 9t strain of VEE virus. This resistance was elicited after administ...
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Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1961-07, Vol.107 (3), p.607-610 |
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container_title | Experimental biology and medicine (Maywood, N.J.) |
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creator | Hearn, Henry J. |
description | Summary
Mice were capable of with standing a large challenge dose of virulent Venezuelan equine encephalomyelitis virus and a substantial challenge dose of eastern equine encephalomyelitis virus after immunization with an attenuated 9t strain of VEE virus. This resistance was elicited after administration of the 9t strain by the intraperitoneal, subcutaneous, and respiratory routes, the latter being accomplished by short exposures to aerosols of the attenuated strain. Rabbits and guinea pigs, which were refractory to infections with EEE virus, were protected against lethal doses of the heterologous virulent VEE virus. |
doi_str_mv | 10.3181/00379727-107-26702 |
format | Article |
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Mice were capable of with standing a large challenge dose of virulent Venezuelan equine encephalomyelitis virus and a substantial challenge dose of eastern equine encephalomyelitis virus after immunization with an attenuated 9t strain of VEE virus. This resistance was elicited after administration of the 9t strain by the intraperitoneal, subcutaneous, and respiratory routes, the latter being accomplished by short exposures to aerosols of the attenuated strain. Rabbits and guinea pigs, which were refractory to infections with EEE virus, were protected against lethal doses of the heterologous virulent VEE virus.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-107-26702</identifier><identifier>PMID: 13712597</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Animals ; Cross Protection ; Encephalitis Virus, Eastern Equine ; Encephalomyelitis ; Encephalomyelitis, Equine - virology ; Encephalomyelitis, Venezuelan Equine ; Horses ; Old Medline</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1961-07, Vol.107 (3), p.607-610</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c341t-746d03796ede1b4103279c66680bc7366ca166642873e57217bec132872d20493</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13712597$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hearn, Henry J.</creatorcontrib><title>Cross–Protection Between Venezuelan Equine Encephalomyelitis and Eastern Equine Encephalomyelitis Virus</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
Mice were capable of with standing a large challenge dose of virulent Venezuelan equine encephalomyelitis virus and a substantial challenge dose of eastern equine encephalomyelitis virus after immunization with an attenuated 9t strain of VEE virus. This resistance was elicited after administration of the 9t strain by the intraperitoneal, subcutaneous, and respiratory routes, the latter being accomplished by short exposures to aerosols of the attenuated strain. Rabbits and guinea pigs, which were refractory to infections with EEE virus, were protected against lethal doses of the heterologous virulent VEE virus.</description><subject>Animals</subject><subject>Cross Protection</subject><subject>Encephalitis Virus, Eastern Equine</subject><subject>Encephalomyelitis</subject><subject>Encephalomyelitis, Equine - virology</subject><subject>Encephalomyelitis, Venezuelan Equine</subject><subject>Horses</subject><subject>Old Medline</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1961</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtOwzAQRS0EoqXwAyxQVuxC_UjsZAlVeEiVYAHdWo4zBVep09qJUFnxD_whX4JDi9h1NZrRmSvdg9A5wVeMZGSMMRO5oCImWMSUC0wP0JCkLI0Zz_NDNOyBuCcG6MT7BcYkFZQfowFhgtA0F0NkJq7x_vvz68k1LejWNDa6gfYdwEYzsPDRQa1sVKw7YyEqrIbVm6qb5QZq0xofKVtFhfItuD3QzLjOn6Kjuao9nO3mCL3cFs-T-3j6ePcwuZ7GmiWkjUXCq74XhwpImRDMqMg15zzDpRaMc61I2BKaCQahDhElaMLCSiuKk5yN0OU2d-WadQe-lUvjNdShBjSdlxkVGcMZCyDdgrpX4GAuV84sldtIgmUvWP4JDgchfwWHp4tdelcuofp_2RkNwHgLePUKctF0zoa2-yJ_AAIjhPo</recordid><startdate>196107</startdate><enddate>196107</enddate><creator>Hearn, Henry J.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196107</creationdate><title>Cross–Protection Between Venezuelan Equine Encephalomyelitis and Eastern Equine Encephalomyelitis Virus</title><author>Hearn, Henry J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c341t-746d03796ede1b4103279c66680bc7366ca166642873e57217bec132872d20493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1961</creationdate><topic>Animals</topic><topic>Cross Protection</topic><topic>Encephalitis Virus, Eastern Equine</topic><topic>Encephalomyelitis</topic><topic>Encephalomyelitis, Equine - virology</topic><topic>Encephalomyelitis, Venezuelan Equine</topic><topic>Horses</topic><topic>Old Medline</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hearn, Henry J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hearn, Henry J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cross–Protection Between Venezuelan Equine Encephalomyelitis and Eastern Equine Encephalomyelitis Virus</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1961-07</date><risdate>1961</risdate><volume>107</volume><issue>3</issue><spage>607</spage><epage>610</epage><pages>607-610</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
Mice were capable of with standing a large challenge dose of virulent Venezuelan equine encephalomyelitis virus and a substantial challenge dose of eastern equine encephalomyelitis virus after immunization with an attenuated 9t strain of VEE virus. This resistance was elicited after administration of the 9t strain by the intraperitoneal, subcutaneous, and respiratory routes, the latter being accomplished by short exposures to aerosols of the attenuated strain. Rabbits and guinea pigs, which were refractory to infections with EEE virus, were protected against lethal doses of the heterologous virulent VEE virus.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>13712597</pmid><doi>10.3181/00379727-107-26702</doi><tpages>4</tpages></addata></record> |
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subjects | Animals Cross Protection Encephalitis Virus, Eastern Equine Encephalomyelitis Encephalomyelitis, Equine - virology Encephalomyelitis, Venezuelan Equine Horses Old Medline |
title | Cross–Protection Between Venezuelan Equine Encephalomyelitis and Eastern Equine Encephalomyelitis Virus |
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