Intravenous pentagastrin as a partial agonist of gastric secretion in man: evidence in favor of the existence of hormonal inhibitory sites

The gastric secretory response to prompt intravenous injection of pentagastrin was investigated in 3 normal subjects and 3 patients with duodenal ulcer. The highest responses to pentagastrin and histamine were correlated. Intravenous pentagastrin in a dose of 0,5 mug per kg could thus achieve the sa...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 1975-01, Vol.68 (1), p.45-49
Hauptverfasser:	Prugh, M F, Schorr, B A, Vlahcevic, Z R, Makhlouf, G M
Format:	Artikel
Sprache:	eng
Schlagworte:	Depression, Chemical Dose-Response Relationship, Drug Duodenal Ulcer - metabolism Gastric Juice - secretion Gastric Mucosa - secretion Gastrins - administration & dosage Gastrins - pharmacology Histamine - administration & dosage Histamine - pharmacology Humans Infusions, Parenteral Injections, Intravenous Injections, Subcutaneous Male Models, Biological Pentagastrin - administration & dosage Pentagastrin - pharmacology Pepsin A - secretion Receptors, Cell Surface Stimulation, Chemical
Online-Zugang:	Volltext
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