Immunosuppression of congenitally athymic (nude) mice with heterologous anti-immunoglobulin heavy-chain antisera

Congenitally athymic (nude) mice have been shown to be far more sensitive than their phenotypically normal littermates to immunosuppression by anti-Ig antisera. Anti-μ suppression of nude mice was seen to result in complete and stable loss of IgM and IgA as well as severe reductions in IgG1 and IgG2...

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Veröffentlicht in:	Cellular immunology 1974-12, Vol.14 (3), p.453-459
Hauptverfasser:	Manning, Dean D., Jutila, John W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Anti-Idiotypic Antibody Formation Immunoglobulin A - biosynthesis Immunoglobulin alpha-Chains Immunoglobulin G - biosynthesis Immunoglobulin gamma-Chains Immunoglobulin Heavy Chains Immunoglobulin M - biosynthesis Immunoglobulin mu-Chains Immunosuppression Mice Mice, Nude - immunology Thymus Gland - immunology
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