Conservation of primary structure in 16S ribosomal RNA
THERE is no doubt that the large ribosomal RNAs play specific roles in ribosome function 1 . Yet the thrust of experimentation during the past 5 years indicates clearly that the biologist tends to view these roles as structural, function being reserved by and large for the ribosomal protein componen...
Gespeichert in:
| Veröffentlicht in: | Nature (London) 1975-03, Vol.254 (5495), p.83-86 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 86 |
|---|---|
| container_issue | 5495 |
| container_start_page | 83 |
| container_title | Nature (London) |
| container_volume | 254 |
| creator | WOESE, CARL R. Fox, GEORGE E. ZABLEN, LAWRENCE UCHIDA, TSUNEKO BONEN, LINDA PECHMAN, KENNETH LEWIS, BOBBY J. STAHL, DAVID |
| description | THERE is no doubt that the large ribosomal RNAs play specific roles in ribosome function
1
. Yet the thrust of experimentation during the past 5 years indicates clearly that the biologist tends to view these roles as structural, function being reserved by and large for the ribosomal protein components
2,3
. Whether or not this prejudice can be maintained remains to be seen. In any case, the existence of an approximate sequence for a 16S rRNA provides a basis for detailed characterisations of this molecule
3,4
. Here we begin to define 16S rRNA function by localising the major conserved regions in the molecule through a comparative analysis of 27 prokaryotic 16S rRNA primary structures. |
| doi_str_mv | 10.1038/254083a0 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_82751106</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>82751106</sourcerecordid><originalsourceid>FETCH-LOGICAL-c312t-97b53a324125b507b70b7abf466232142ade1d9e327d46427e82166d03ceeffa3</originalsourceid><addsrcrecordid>eNplkF1LwzAYhYMoc07BPyD0SvSi-r5JmqSXY_gFQ8GP65C0qXS0zUzagf_e6iYIXp2L5-HAOYScIlwhMHVNMw6KGdgjU-RSpFwouU-mAFSlIxCH5CjGFQBkKPmETBBUnkM-JWLhu-jCxvS17xJfJetQtyZ8JrEPQ9EPwSV1l6B4SUJtffStaZLnx_kxOahME93JLmfk7fbmdXGfLp_uHhbzZVowpH2aS5sxwyhHmtkMpJVgpbEVF4Iyipya0mGZO0ZlyQWn0imKQpTACueqyrAZOd_2roP_GFzsdVvHwjWN6ZwfolZUZoggRvFiKxbBxxhcpXdDNIL-vkj_XjSqZ7vOwbau_CP-fDLyyy2PI-neXdArP4RunPm_6wvVaWvH</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>82751106</pqid></control><display><type>article</type><title>Conservation of primary structure in 16S ribosomal RNA</title><source>MEDLINE</source><source>SpringerLink Journals</source><source>Nature Journals Online</source><creator>WOESE, CARL R. ; Fox, GEORGE E. ; ZABLEN, LAWRENCE ; UCHIDA, TSUNEKO ; BONEN, LINDA ; PECHMAN, KENNETH ; LEWIS, BOBBY J. ; STAHL, DAVID</creator><creatorcontrib>WOESE, CARL R. ; Fox, GEORGE E. ; ZABLEN, LAWRENCE ; UCHIDA, TSUNEKO ; BONEN, LINDA ; PECHMAN, KENNETH ; LEWIS, BOBBY J. ; STAHL, DAVID</creatorcontrib><description>THERE is no doubt that the large ribosomal RNAs play specific roles in ribosome function
1
. Yet the thrust of experimentation during the past 5 years indicates clearly that the biologist tends to view these roles as structural, function being reserved by and large for the ribosomal protein components
2,3
. Whether or not this prejudice can be maintained remains to be seen. In any case, the existence of an approximate sequence for a 16S rRNA provides a basis for detailed characterisations of this molecule
3,4
. Here we begin to define 16S rRNA function by localising the major conserved regions in the molecule through a comparative analysis of 27 prokaryotic 16S rRNA primary structures.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/254083a0</identifier><identifier>PMID: 1089909</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Base Sequence ; Escherichia coli - analysis ; Humanities and Social Sciences ; Hydrolysis ; letter ; multidisciplinary ; Oligonucleotides - analysis ; Phylogeny ; Ribonucleases ; RNA, Bacterial - analysis ; RNA, Ribosomal - analysis ; Science ; Science (multidisciplinary) ; Space life sciences</subject><ispartof>Nature (London), 1975-03, Vol.254 (5495), p.83-86</ispartof><rights>Springer Nature Limited 1975</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c312t-97b53a324125b507b70b7abf466232142ade1d9e327d46427e82166d03ceeffa3</citedby><cites>FETCH-LOGICAL-c312t-97b53a324125b507b70b7abf466232142ade1d9e327d46427e82166d03ceeffa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/254083a0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/254083a0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1089909$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>WOESE, CARL R.</creatorcontrib><creatorcontrib>Fox, GEORGE E.</creatorcontrib><creatorcontrib>ZABLEN, LAWRENCE</creatorcontrib><creatorcontrib>UCHIDA, TSUNEKO</creatorcontrib><creatorcontrib>BONEN, LINDA</creatorcontrib><creatorcontrib>PECHMAN, KENNETH</creatorcontrib><creatorcontrib>LEWIS, BOBBY J.</creatorcontrib><creatorcontrib>STAHL, DAVID</creatorcontrib><title>Conservation of primary structure in 16S ribosomal RNA</title><title>Nature (London)</title><addtitle>Nature</addtitle><addtitle>Nature</addtitle><description>THERE is no doubt that the large ribosomal RNAs play specific roles in ribosome function
1
. Yet the thrust of experimentation during the past 5 years indicates clearly that the biologist tends to view these roles as structural, function being reserved by and large for the ribosomal protein components
2,3
. Whether or not this prejudice can be maintained remains to be seen. In any case, the existence of an approximate sequence for a 16S rRNA provides a basis for detailed characterisations of this molecule
3,4
. Here we begin to define 16S rRNA function by localising the major conserved regions in the molecule through a comparative analysis of 27 prokaryotic 16S rRNA primary structures.</description><subject>Base Sequence</subject><subject>Escherichia coli - analysis</subject><subject>Humanities and Social Sciences</subject><subject>Hydrolysis</subject><subject>letter</subject><subject>multidisciplinary</subject><subject>Oligonucleotides - analysis</subject><subject>Phylogeny</subject><subject>Ribonucleases</subject><subject>RNA, Bacterial - analysis</subject><subject>RNA, Ribosomal - analysis</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Space life sciences</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1975</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkF1LwzAYhYMoc07BPyD0SvSi-r5JmqSXY_gFQ8GP65C0qXS0zUzagf_e6iYIXp2L5-HAOYScIlwhMHVNMw6KGdgjU-RSpFwouU-mAFSlIxCH5CjGFQBkKPmETBBUnkM-JWLhu-jCxvS17xJfJetQtyZ8JrEPQ9EPwSV1l6B4SUJtffStaZLnx_kxOahME93JLmfk7fbmdXGfLp_uHhbzZVowpH2aS5sxwyhHmtkMpJVgpbEVF4Iyipya0mGZO0ZlyQWn0imKQpTACueqyrAZOd_2roP_GFzsdVvHwjWN6ZwfolZUZoggRvFiKxbBxxhcpXdDNIL-vkj_XjSqZ7vOwbau_CP-fDLyyy2PI-neXdArP4RunPm_6wvVaWvH</recordid><startdate>19750306</startdate><enddate>19750306</enddate><creator>WOESE, CARL R.</creator><creator>Fox, GEORGE E.</creator><creator>ZABLEN, LAWRENCE</creator><creator>UCHIDA, TSUNEKO</creator><creator>BONEN, LINDA</creator><creator>PECHMAN, KENNETH</creator><creator>LEWIS, BOBBY J.</creator><creator>STAHL, DAVID</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19750306</creationdate><title>Conservation of primary structure in 16S ribosomal RNA</title><author>WOESE, CARL R. ; Fox, GEORGE E. ; ZABLEN, LAWRENCE ; UCHIDA, TSUNEKO ; BONEN, LINDA ; PECHMAN, KENNETH ; LEWIS, BOBBY J. ; STAHL, DAVID</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c312t-97b53a324125b507b70b7abf466232142ade1d9e327d46427e82166d03ceeffa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1975</creationdate><topic>Base Sequence</topic><topic>Escherichia coli - analysis</topic><topic>Humanities and Social Sciences</topic><topic>Hydrolysis</topic><topic>letter</topic><topic>multidisciplinary</topic><topic>Oligonucleotides - analysis</topic><topic>Phylogeny</topic><topic>Ribonucleases</topic><topic>RNA, Bacterial - analysis</topic><topic>RNA, Ribosomal - analysis</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Space life sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>WOESE, CARL R.</creatorcontrib><creatorcontrib>Fox, GEORGE E.</creatorcontrib><creatorcontrib>ZABLEN, LAWRENCE</creatorcontrib><creatorcontrib>UCHIDA, TSUNEKO</creatorcontrib><creatorcontrib>BONEN, LINDA</creatorcontrib><creatorcontrib>PECHMAN, KENNETH</creatorcontrib><creatorcontrib>LEWIS, BOBBY J.</creatorcontrib><creatorcontrib>STAHL, DAVID</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>WOESE, CARL R.</au><au>Fox, GEORGE E.</au><au>ZABLEN, LAWRENCE</au><au>UCHIDA, TSUNEKO</au><au>BONEN, LINDA</au><au>PECHMAN, KENNETH</au><au>LEWIS, BOBBY J.</au><au>STAHL, DAVID</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Conservation of primary structure in 16S ribosomal RNA</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1975-03-06</date><risdate>1975</risdate><volume>254</volume><issue>5495</issue><spage>83</spage><epage>86</epage><pages>83-86</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>THERE is no doubt that the large ribosomal RNAs play specific roles in ribosome function
1
. Yet the thrust of experimentation during the past 5 years indicates clearly that the biologist tends to view these roles as structural, function being reserved by and large for the ribosomal protein components
2,3
. Whether or not this prejudice can be maintained remains to be seen. In any case, the existence of an approximate sequence for a 16S rRNA provides a basis for detailed characterisations of this molecule
3,4
. Here we begin to define 16S rRNA function by localising the major conserved regions in the molecule through a comparative analysis of 27 prokaryotic 16S rRNA primary structures.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>1089909</pmid><doi>10.1038/254083a0</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-0836 |
| ispartof | Nature (London), 1975-03, Vol.254 (5495), p.83-86 |
| issn | 0028-0836 1476-4687 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_82751106 |
| source | MEDLINE; SpringerLink Journals; Nature Journals Online |
| subjects | Base Sequence Escherichia coli - analysis Humanities and Social Sciences Hydrolysis letter multidisciplinary Oligonucleotides - analysis Phylogeny Ribonucleases RNA, Bacterial - analysis RNA, Ribosomal - analysis Science Science (multidisciplinary) Space life sciences |
| title | Conservation of primary structure in 16S ribosomal RNA |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T07%3A35%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Conservation%20of%20primary%20structure%20in%2016S%20ribosomal%20RNA&rft.jtitle=Nature%20(London)&rft.au=WOESE,%20CARL%20R.&rft.date=1975-03-06&rft.volume=254&rft.issue=5495&rft.spage=83&rft.epage=86&rft.pages=83-86&rft.issn=0028-0836&rft.eissn=1476-4687&rft_id=info:doi/10.1038/254083a0&rft_dat=%3Cproquest_cross%3E82751106%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=82751106&rft_id=info:pmid/1089909&rfr_iscdi=true |