Effects of Δ 9-tetrahydrocannabinol on the levels of cyclic adenosine 3',5'-monophosphate in mouse brain

The effects of intraperitoneal injections of various doses of Δ 9-tetrahydrocannabinol ( Δ 9-THC) on brain levels of cyclic adenosine 3',5'-monophosphate (cyclic AMP) have been studied in mice. Doses of Δ 9-THC in the range of 0.1 to 1.0 mg/kg cause a 50–160 per cent elevation of cyclic AM...

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Veröffentlicht in:	Biochemical pharmacology 1974-07, Vol.23 (13), p.1817-1825
Hauptverfasser:	Dolby, Thomas W., Kleinsmith, Lewis J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclases - metabolism Animals Brain - drug effects Brain - metabolism Cannabis - pharmacology Cattle Cerebellum - enzymology Cerebral Cortex - metabolism Cyclic AMP - metabolism Dose-Response Relationship, Drug Dronabinol - pharmacology Hypothalamus - enzymology Medulla Oblongata - enzymology Mice Microwaves Muscles - enzymology Organ Specificity Phosphoric Diester Hydrolases - metabolism Postmortem Changes Protein Kinases - metabolism
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