A Nonsteroidal Androgen

A Nonsteroidal Androgen

2-Acetyl-7-oxo-1, 2, 3, 4, 4a, 4b, 5, 6, 7, 9, 10, 10a-dodecahydrophenanthrene possesses androgenic activity when applied directly to the chick's comb. This action is in addition to the antiandrogenic activity previously reported for this compound. This is the first demonstration of androgenic...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1960-04, Vol.131 (3407), p.1096-1096
1. Verfasser: Dorfman, Ralph I.
Format: Artikel
Sprache:eng
Schlagworte:
Androgen Antagonists
Androgens - pharmacology
Cell Nucleus
Lesions
Old Medline
Testosterone
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Zusammenfassung:2-Acetyl-7-oxo-1, 2, 3, 4, 4a, 4b, 5, 6, 7, 9, 10, 10a-dodecahydrophenanthrene possesses androgenic activity when applied directly to the chick's comb. This action is in addition to the antiandrogenic activity previously reported for this compound. This is the first demonstration of androgenic activity by a compound not possessing the steroid nucleus.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.131.3407.1096