Slopes of dose-response curves to norepinephrine in isolated strips of the cat's spleen

In isolated strips of the spleen capsule, the shifts to the right in dose-response curves to norepinephrine obtained in the presence of phentolamine were accompanied by an increase in the slope of the dose-response curve. This phenomenon was observed both in normal and in reserpine-pretreated tissue...

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Veröffentlicht in:	European journal of pharmacology 1974-12, Vol.29 (2), p.328-338
Hauptverfasser:	Granata, Antonio R., Stefano, Francisco J.E., Langer, Salomón Z.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cats Cocaine Cocaine - pharmacology Denervation Dose-Response Relationship, Drug In Vitro Techniques Norepinephrine Norepinephrine - pharmacology Phentolamine Phentolamine - pharmacology Reserpine - pharmacology sloped of dose-response curves Spleen - drug effects Spleen - innervation Spleen capsule Time Factors Tritium
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