Investigation of Rose Bengal Conjugation.

Investigation of Rose Bengal Conjugation.

Summary 1. Metabolites of Rose Bengal could not be demonstrated in human bile, serum or urine or in extracts from rat liver by a variety of systems involving paper and column chromatography and electrophoresis. 2. Conjugation with cystine-S35 or glucuronic acid was not demonstrable. 3. It was conclu...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1960-08, Vol.104 (4), p.650-653
Hauptverfasser: Kubin, R. H., Grodsky, G. M., Carbone, J. V.
Format: Artikel
Sprache:eng
Schlagworte:
Fluorescent Dyes - chemistry
Old Medline
Physiological Phenomena
Rose Bengal
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Zusammenfassung:Summary 1. Metabolites of Rose Bengal could not be demonstrated in human bile, serum or urine or in extracts from rat liver by a variety of systems involving paper and column chromatography and electrophoresis. 2. Conjugation with cystine-S35 or glucuronic acid was not demonstrable. 3. It was concluded that Rose Bengal is not conjugated by the liver in the same form reported for bilirubin (glucuronides) or bromsulfalein (mercapticles).
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-104-25939