Immunopathogenicity and oncogenicity of murine leukemia viruses. I. Induction of immunologic disease and lymphoma in (BALB-c times NZB)F1 mice by Scripps leukemia virus

This report clearly demonstrates that a systemic lupus erythematosus (SLE)-like syndrome and lymphoma can be induced in immunologically normal (BALB/c x NZB)F(1) mice by infection of neonates with a murine leukemia virus (MuLV) (Scripps leukemia virus [SLV] 60A) isolated from NZB lymphoblasts. SLV 6...

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Veröffentlicht in:	The Journal of experimental medicine 1974-10, Vol.140 (4), p.1028-1048
Hauptverfasser:	Croker, Jr, B P, del Villano, B C, Jensen, F C, Lerner, R A, Dixon, F J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Antinuclear - analysis Antibodies, Viral - analysis Antibody Formation Antigens, Viral Disease Models, Animal Female Glomerulonephritis - etiology Glomerulonephritis - immunology Immune Complex Diseases - etiology Immune Complex Diseases - immunology Leukemia Virus, Murine - immunology Leukemia Virus, Murine - isolation & purification Lupus Erythematosus, Systemic Lymph Nodes - microbiology Lymph Nodes - ultrastructure Lymphoma - etiology Lymphoma - microbiology Lymphoma - pathology Male Mice Mice, Inbred BALB C Mice, Inbred NZB Sex Factors Spleen - microbiology Thymus Gland - pathology
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