The role of calcium ions in initiating transformation of lymphocytes

TRANSFORMATION of lymphocytes by antigens and by nonspecific mitogens (lectins and anti-immunoglobulin sera) is a consequence of the binding of the mitogen to specific receptors on the cell surface 1–3 . The receptors rapidly form clusters (‘patches’) which may aggregate into polar ‘caps’ 4 at highe...

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Veröffentlicht in:	Nature (London) 1974-01, Vol.251 (5473), p.324-327
Hauptverfasser:	MAINO, VERNON C., GREEN, N. MICHAEL, CRUMPTON, MICHAEL J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - pharmacology Calcium - physiology Carboxylic Acids - pharmacology Cell Membrane - ultrastructure Depression, Chemical DNA - biosynthesis Endoplasmic Reticulum - ultrastructure Humanities and Social Sciences Iontophoresis Lectins - pharmacology letter Lymphocyte Activation - drug effects Lymphocytes - drug effects Lymphocytes - metabolism Lymphocytes - ultrastructure Microscopy, Electron Mitochondria - ultrastructure multidisciplinary Science Science (multidisciplinary) Streptomyces Swine Thymidine - metabolism Tritium
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