Evaluation of ischemic damage to rat liver mitochondria using the Krebs-cycle

Pyruvate catabolism is directed towards citrate condensation rather than ketonebody formation both in normal and in ischemic rat liver mitochondria in the presence of an ADP generating system and l-malate. Although the phosphorylating capacity of ischemic liver mitochondria is greatly reduced, their...

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Veröffentlicht in:	The Journal of surgical research 1974-09, Vol.17 (3), p.204-209
Hauptverfasser:	Daniel, Anna M., Beaudoin, Jean-Guy
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetoacetates - biosynthesis Adenosine Triphosphate - biosynthesis Animals Buffers Carbon Radioisotopes Chromatography, Paper Citrates - metabolism Citric Acid Cycle Fumarates - metabolism Hydroxybutyrates - biosynthesis In Vitro Techniques Ischemia - metabolism Ketoglutaric Acids - metabolism Ketone Bodies - biosynthesis Liver - blood supply Malates - metabolism Mitochondria, Liver - metabolism Oxidation-Reduction Pyruvates - metabolism Rats Succinates - metabolism Temperature
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