The carbohydrate and ester sulfate content of mucosal biopsies in health and in patients with duodenal ulcer
The carbohydrate and ester sulfate contents of duodenal mucosal biopsies from patients with duodenal ulcer and from control subjects have been determined by gas—liquid chromatography. The net amounts and molar ratios (to glucosamine) of fucose, galactose, mannose, glucose, N-acetylglucosamine, N-ace...
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| Veröffentlicht in: | Clinica chimica acta 1974-11, Vol.56 (3), p.255-259 |
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| container_title | Clinica chimica acta |
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| creator | Andre, Françoise Bouhours, Daniele Andre, Claude Descos, Françoise Lambert, Rene |
| description | The carbohydrate and ester sulfate contents of duodenal mucosal biopsies from patients with duodenal ulcer and from control subjects have been determined by gas—liquid chromatography. The net amounts and molar ratios (to glucosamine) of fucose, galactose, mannose, glucose,
N-acetylglucosamine,
N-acetylgalactosamine and sulfate were similar in both groups. These findings suggest that sulfated glycoproteins, which inhibit the proteolytic activity of pepsin, are not involved in the pathogenesis of duodenal ulcer. |
| doi_str_mv | 10.1016/0009-8981(74)90137-5 |
| format | Article |
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N-acetylglucosamine,
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N-acetylglucosamine,
N-acetylgalactosamine and sulfate were similar in both groups. These findings suggest that sulfated glycoproteins, which inhibit the proteolytic activity of pepsin, are not involved in the pathogenesis of duodenal ulcer.</description><subject>Biopsy</subject><subject>Carbohydrate Metabolism</subject><subject>Chromatography, Gas</subject><subject>Chromatography, Ion Exchange</subject><subject>Duodenal Ulcer - metabolism</subject><subject>Fucose - metabolism</subject><subject>Galactosamine - analogs & derivatives</subject><subject>Galactosamine - metabolism</subject><subject>Galactose - metabolism</subject><subject>Glucosamine - analogs & derivatives</subject><subject>Glucosamine - metabolism</subject><subject>Glucose - metabolism</subject><subject>Glycoproteins - metabolism</subject><subject>Humans</subject><subject>Intestinal Mucosa - metabolism</subject><subject>Mannose - metabolism</subject><subject>Sulfuric Acid Esters - metabolism</subject><issn>0009-8981</issn><issn>1873-3492</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1974</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE9LAzEQxYMotVa_gUJOoofVZDe72VwEKf6Dgpd6DtlkQiPbTU12lX57s7b06GmYee_NMD-ELim5o4RW94QQkdWipjec3QpCC56VR2hKa15kBRP5MZoeLKfoLMbP1DJS0QmaMEbrvKJT1C5XgLUKjV9tTVA9YNUZDLGHgOPQ2nGifddD12Nv8XrQPqoWN85vooOIXYdXoNp-9ZdL3Ub1Lpkj_nFpaAZvoEuBodUQztGJVW2Ei32doY_np-X8NVu8v7zNHxeZLkreZ4YZEJQrawVUBecllKUuWE6EqitNqWHC2NyY3ApalpZaxqpGKVCkaYBwW8zQ9W7vJvivIT0j1y5qaFvVgR-irHMmEqUqGdnOqIOPMYCVm-DWKmwlJXKELEeCciQoOZN_kGWZYlf7_UOzBnMI7akm_WGnQ3ry20GQUScoGowLoHtpvPv_wC-CVY17</recordid><startdate>19741108</startdate><enddate>19741108</enddate><creator>Andre, Françoise</creator><creator>Bouhours, Daniele</creator><creator>Andre, Claude</creator><creator>Descos, Françoise</creator><creator>Lambert, Rene</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19741108</creationdate><title>The carbohydrate and ester sulfate content of mucosal biopsies in health and in patients with duodenal ulcer</title><author>Andre, Françoise ; Bouhours, Daniele ; Andre, Claude ; Descos, Françoise ; Lambert, Rene</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-d4de917aff9e63775e55c34209a86c11d49df2dd2f9155f1f446baaea0bbe07f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1974</creationdate><topic>Biopsy</topic><topic>Carbohydrate Metabolism</topic><topic>Chromatography, Gas</topic><topic>Chromatography, Ion Exchange</topic><topic>Duodenal Ulcer - metabolism</topic><topic>Fucose - metabolism</topic><topic>Galactosamine - analogs & derivatives</topic><topic>Galactosamine - metabolism</topic><topic>Galactose - metabolism</topic><topic>Glucosamine - analogs & derivatives</topic><topic>Glucosamine - metabolism</topic><topic>Glucose - metabolism</topic><topic>Glycoproteins - metabolism</topic><topic>Humans</topic><topic>Intestinal Mucosa - metabolism</topic><topic>Mannose - metabolism</topic><topic>Sulfuric Acid Esters - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Andre, Françoise</creatorcontrib><creatorcontrib>Bouhours, Daniele</creatorcontrib><creatorcontrib>Andre, Claude</creatorcontrib><creatorcontrib>Descos, Françoise</creatorcontrib><creatorcontrib>Lambert, Rene</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinica chimica acta</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Andre, Françoise</au><au>Bouhours, Daniele</au><au>Andre, Claude</au><au>Descos, Françoise</au><au>Lambert, Rene</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The carbohydrate and ester sulfate content of mucosal biopsies in health and in patients with duodenal ulcer</atitle><jtitle>Clinica chimica acta</jtitle><addtitle>Clin Chim Acta</addtitle><date>1974-11-08</date><risdate>1974</risdate><volume>56</volume><issue>3</issue><spage>255</spage><epage>259</epage><pages>255-259</pages><issn>0009-8981</issn><eissn>1873-3492</eissn><abstract>The carbohydrate and ester sulfate contents of duodenal mucosal biopsies from patients with duodenal ulcer and from control subjects have been determined by gas—liquid chromatography. The net amounts and molar ratios (to glucosamine) of fucose, galactose, mannose, glucose,
N-acetylglucosamine,
N-acetylgalactosamine and sulfate were similar in both groups. These findings suggest that sulfated glycoproteins, which inhibit the proteolytic activity of pepsin, are not involved in the pathogenesis of duodenal ulcer.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>4418261</pmid><doi>10.1016/0009-8981(74)90137-5</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0009-8981 |
| ispartof | Clinica chimica acta, 1974-11, Vol.56 (3), p.255-259 |
| issn | 0009-8981 1873-3492 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Biopsy Carbohydrate Metabolism Chromatography, Gas Chromatography, Ion Exchange Duodenal Ulcer - metabolism Fucose - metabolism Galactosamine - analogs & derivatives Galactosamine - metabolism Galactose - metabolism Glucosamine - analogs & derivatives Glucosamine - metabolism Glucose - metabolism Glycoproteins - metabolism Humans Intestinal Mucosa - metabolism Mannose - metabolism Sulfuric Acid Esters - metabolism |
| title | The carbohydrate and ester sulfate content of mucosal biopsies in health and in patients with duodenal ulcer |
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