Synthesis and biological activity of DL-3-(5-benzimidazolyl)-2-methylalanine

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of medicinal chemistry 1974-11, Vol.17 (11), p.1223-1225
Hauptverfasser: Zenker, Nicolas, Morgenroth, Victor H, Wright, Jeremy
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1225
container_issue 11
container_start_page 1223
container_title Journal of medicinal chemistry
container_volume 17
creator Zenker, Nicolas
Morgenroth, Victor H
Wright, Jeremy
description
doi_str_mv 10.1021/jm00257a017
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_82493933</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>82493933</sourcerecordid><originalsourceid>FETCH-LOGICAL-a354t-192ef7fb9d3ec652fa19d4fff9cc645e4c45635c56fce76a062deacb2e6dcb4e3</originalsourceid><addsrcrecordid>eNptkMlLw0AUhwdRtC4nz0JOLsjo7DFHaa1VAgrW8zCZvLFTs9RMKsa_3khL8eDpwft9vOVD6JiSK0oYvZ6XhDAZG0LjLTSgkhEsbojYRoO-zzBTjO-h_RDmhBBOGd9Fu4JKLhI-QOlLV7UzCD5EpsqjzNdF_eatKSJjW__p2y6qXTRKMcfnEmdQffvS5-a7LrriAjNcQjvrClOYyldwiHacKQIcresBeh3fTYcTnD7dPwxvU2y4FC2mCQMXuyzJOVglmTM0yYVzLrFWCQnCCqm4tFI5C7EyRLEcjM0YqNxmAvgBOl3NXTT1xxJCq0sfLBT9FVAvg75h_W8J5z14uQJtU4fQgNOLxpem6TQl-ted_uOup0_WY5dZCfmGXcvqc7zKfWjhaxOb5l2rmMdST59f9GiaJuMJi_Vjz5-teGODntfLpuql_Lv5Byw2hV8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>82493933</pqid></control><display><type>article</type><title>Synthesis and biological activity of DL-3-(5-benzimidazolyl)-2-methylalanine</title><source>MEDLINE</source><source>ACS Publications</source><creator>Zenker, Nicolas ; Morgenroth, Victor H ; Wright, Jeremy</creator><creatorcontrib>Zenker, Nicolas ; Morgenroth, Victor H ; Wright, Jeremy</creatorcontrib><identifier>ISSN: 0022-2623</identifier><identifier>EISSN: 1520-4804</identifier><identifier>DOI: 10.1021/jm00257a017</identifier><identifier>PMID: 4153493</identifier><language>eng</language><publisher>United States: American Chemical Society</publisher><subject>Alanine - analogs &amp; derivatives ; Alanine - chemical synthesis ; Alanine - pharmacology ; Animals ; Benzimidazoles - chemical synthesis ; Benzimidazoles - pharmacology ; Brain Chemistry - drug effects ; Depression, Chemical ; Dopamine - analysis ; Epinephrine - analysis ; Kinetics ; Male ; Myocardium - analysis ; Organ Specificity ; Protein Binding - drug effects ; Rats ; Serotonin - analysis ; Time Factors ; Tyrosine - antagonists &amp; inhibitors ; Tyrosine - metabolism ; Tyrosine 3-Monooxygenase - antagonists &amp; inhibitors ; Tyrosine 3-Monooxygenase - metabolism</subject><ispartof>Journal of medicinal chemistry, 1974-11, Vol.17 (11), p.1223-1225</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a354t-192ef7fb9d3ec652fa19d4fff9cc645e4c45635c56fce76a062deacb2e6dcb4e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/jm00257a017$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/jm00257a017$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,776,780,2751,27055,27903,27904,56716,56766</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4153493$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zenker, Nicolas</creatorcontrib><creatorcontrib>Morgenroth, Victor H</creatorcontrib><creatorcontrib>Wright, Jeremy</creatorcontrib><title>Synthesis and biological activity of DL-3-(5-benzimidazolyl)-2-methylalanine</title><title>Journal of medicinal chemistry</title><addtitle>J. Med. Chem</addtitle><subject>Alanine - analogs &amp; derivatives</subject><subject>Alanine - chemical synthesis</subject><subject>Alanine - pharmacology</subject><subject>Animals</subject><subject>Benzimidazoles - chemical synthesis</subject><subject>Benzimidazoles - pharmacology</subject><subject>Brain Chemistry - drug effects</subject><subject>Depression, Chemical</subject><subject>Dopamine - analysis</subject><subject>Epinephrine - analysis</subject><subject>Kinetics</subject><subject>Male</subject><subject>Myocardium - analysis</subject><subject>Organ Specificity</subject><subject>Protein Binding - drug effects</subject><subject>Rats</subject><subject>Serotonin - analysis</subject><subject>Time Factors</subject><subject>Tyrosine - antagonists &amp; inhibitors</subject><subject>Tyrosine - metabolism</subject><subject>Tyrosine 3-Monooxygenase - antagonists &amp; inhibitors</subject><subject>Tyrosine 3-Monooxygenase - metabolism</subject><issn>0022-2623</issn><issn>1520-4804</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1974</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkMlLw0AUhwdRtC4nz0JOLsjo7DFHaa1VAgrW8zCZvLFTs9RMKsa_3khL8eDpwft9vOVD6JiSK0oYvZ6XhDAZG0LjLTSgkhEsbojYRoO-zzBTjO-h_RDmhBBOGd9Fu4JKLhI-QOlLV7UzCD5EpsqjzNdF_eatKSJjW__p2y6qXTRKMcfnEmdQffvS5-a7LrriAjNcQjvrClOYyldwiHacKQIcresBeh3fTYcTnD7dPwxvU2y4FC2mCQMXuyzJOVglmTM0yYVzLrFWCQnCCqm4tFI5C7EyRLEcjM0YqNxmAvgBOl3NXTT1xxJCq0sfLBT9FVAvg75h_W8J5z14uQJtU4fQgNOLxpem6TQl-ted_uOup0_WY5dZCfmGXcvqc7zKfWjhaxOb5l2rmMdST59f9GiaJuMJi_Vjz5-teGODntfLpuql_Lv5Byw2hV8</recordid><startdate>19741101</startdate><enddate>19741101</enddate><creator>Zenker, Nicolas</creator><creator>Morgenroth, Victor H</creator><creator>Wright, Jeremy</creator><general>American Chemical Society</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19741101</creationdate><title>Synthesis and biological activity of DL-3-(5-benzimidazolyl)-2-methylalanine</title><author>Zenker, Nicolas ; Morgenroth, Victor H ; Wright, Jeremy</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a354t-192ef7fb9d3ec652fa19d4fff9cc645e4c45635c56fce76a062deacb2e6dcb4e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1974</creationdate><topic>Alanine - analogs &amp; derivatives</topic><topic>Alanine - chemical synthesis</topic><topic>Alanine - pharmacology</topic><topic>Animals</topic><topic>Benzimidazoles - chemical synthesis</topic><topic>Benzimidazoles - pharmacology</topic><topic>Brain Chemistry - drug effects</topic><topic>Depression, Chemical</topic><topic>Dopamine - analysis</topic><topic>Epinephrine - analysis</topic><topic>Kinetics</topic><topic>Male</topic><topic>Myocardium - analysis</topic><topic>Organ Specificity</topic><topic>Protein Binding - drug effects</topic><topic>Rats</topic><topic>Serotonin - analysis</topic><topic>Time Factors</topic><topic>Tyrosine - antagonists &amp; inhibitors</topic><topic>Tyrosine - metabolism</topic><topic>Tyrosine 3-Monooxygenase - antagonists &amp; inhibitors</topic><topic>Tyrosine 3-Monooxygenase - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zenker, Nicolas</creatorcontrib><creatorcontrib>Morgenroth, Victor H</creatorcontrib><creatorcontrib>Wright, Jeremy</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of medicinal chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zenker, Nicolas</au><au>Morgenroth, Victor H</au><au>Wright, Jeremy</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis and biological activity of DL-3-(5-benzimidazolyl)-2-methylalanine</atitle><jtitle>Journal of medicinal chemistry</jtitle><addtitle>J. Med. Chem</addtitle><date>1974-11-01</date><risdate>1974</risdate><volume>17</volume><issue>11</issue><spage>1223</spage><epage>1225</epage><pages>1223-1225</pages><issn>0022-2623</issn><eissn>1520-4804</eissn><cop>United States</cop><pub>American Chemical Society</pub><pmid>4153493</pmid><doi>10.1021/jm00257a017</doi><tpages>3</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0022-2623
ispartof Journal of medicinal chemistry, 1974-11, Vol.17 (11), p.1223-1225
issn 0022-2623
1520-4804
language eng
recordid cdi_proquest_miscellaneous_82493933
source MEDLINE; ACS Publications
subjects Alanine - analogs & derivatives
Alanine - chemical synthesis
Alanine - pharmacology
Animals
Benzimidazoles - chemical synthesis
Benzimidazoles - pharmacology
Brain Chemistry - drug effects
Depression, Chemical
Dopamine - analysis
Epinephrine - analysis
Kinetics
Male
Myocardium - analysis
Organ Specificity
Protein Binding - drug effects
Rats
Serotonin - analysis
Time Factors
Tyrosine - antagonists & inhibitors
Tyrosine - metabolism
Tyrosine 3-Monooxygenase - antagonists & inhibitors
Tyrosine 3-Monooxygenase - metabolism
title Synthesis and biological activity of DL-3-(5-benzimidazolyl)-2-methylalanine
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T10%3A19%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Synthesis%20and%20biological%20activity%20of%20DL-3-(5-benzimidazolyl)-2-methylalanine&rft.jtitle=Journal%20of%20medicinal%20chemistry&rft.au=Zenker,%20Nicolas&rft.date=1974-11-01&rft.volume=17&rft.issue=11&rft.spage=1223&rft.epage=1225&rft.pages=1223-1225&rft.issn=0022-2623&rft.eissn=1520-4804&rft_id=info:doi/10.1021/jm00257a017&rft_dat=%3Cproquest_cross%3E82493933%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=82493933&rft_id=info:pmid/4153493&rfr_iscdi=true