Synthesis of alkyl-substituted .alpha.,.beta.-unsaturated .gamma.-lactones as potential antitumor agents
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Veröffentlicht in: | Journal of medicinal chemistry 1974-08, Vol.17 (8), p.840-843 |
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container_title | Journal of medicinal chemistry |
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creator | Howie, Gary A Manni, Peter E Cassady, John M |
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doi_str_mv | 10.1021/jm00254a012 |
format | Article |
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Chem</addtitle><subject>Animals</subject><subject>Antineoplastic Agents - chemical synthesis</subject><subject>Antineoplastic Agents - therapeutic use</subject><subject>Carcinoma</subject><subject>Cell Line</subject><subject>Fatty Acids, Unsaturated - chemical synthesis</subject><subject>Fatty Acids, Unsaturated - therapeutic use</subject><subject>Humans</subject><subject>Lactones - chemical synthesis</subject><subject>Lactones - therapeutic use</subject><subject>Leukemia L1210 - drug therapy</subject><subject>Mice</subject><subject>Mouth Neoplasms</subject><subject>Structure-Activity Relationship</subject><issn>0022-2623</issn><issn>1520-4804</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1974</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkEtPG0EQhEdREDgkp5yR9pQcyG7muY9jZHBAsgUSRDmOetZtvGYfZnpWwv8-Q2whDpxaqvqqWirGvgqeCS7Fz03HuTQauJAf2EQYyVNdcv2RTaIuU5lLdcI-EW0450pIdcyOdamNKooJW9_t-rBGaigZVgm0j7s2pdFRaMIYcJlk0G7XkP3IHAbI0rEnCKOH_9YDdF3UWqjD0CMlQMl2CNiHBtoE-peKbvAJPESJPrOjFbSEXw73lP2ZXd5Pr9L5ze_r6a95ClrykBa109zVoHKjuFZSSOGWpjIGsUCJuqxWTurSQVEtUVVaFJWTeS7rmMoNCHXKvu17t354GpGC7RqqsW2hx2EkW8a00JWJ4PkerP1A5HFlt77pwO-s4PZlV_tm10ifHWpH1-HylT0MGf107zcU8PnVBv9o80IVxt7f3tnFdJb_vVhc2Wnkv-95qMluhtH3cZR3P_8DWuiOug</recordid><startdate>19740801</startdate><enddate>19740801</enddate><creator>Howie, Gary A</creator><creator>Manni, Peter E</creator><creator>Cassady, John M</creator><general>American Chemical Society</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19740801</creationdate><title>Synthesis of alkyl-substituted .alpha.,.beta.-unsaturated .gamma.-lactones as potential antitumor agents</title><author>Howie, Gary A ; Manni, Peter E ; Cassady, John M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a420t-7cb40bca36530432121bd5955ee7e2e489fb248ba79de394179b2662c40b65a13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1974</creationdate><topic>Animals</topic><topic>Antineoplastic Agents - chemical synthesis</topic><topic>Antineoplastic Agents - therapeutic use</topic><topic>Carcinoma</topic><topic>Cell Line</topic><topic>Fatty Acids, Unsaturated - chemical synthesis</topic><topic>Fatty Acids, Unsaturated - therapeutic use</topic><topic>Humans</topic><topic>Lactones - chemical synthesis</topic><topic>Lactones - therapeutic use</topic><topic>Leukemia L1210 - drug therapy</topic><topic>Mice</topic><topic>Mouth Neoplasms</topic><topic>Structure-Activity Relationship</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Howie, Gary A</creatorcontrib><creatorcontrib>Manni, Peter E</creatorcontrib><creatorcontrib>Cassady, John M</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of medicinal chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Howie, Gary A</au><au>Manni, Peter E</au><au>Cassady, John M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis of alkyl-substituted .alpha.,.beta.-unsaturated .gamma.-lactones as potential antitumor agents</atitle><jtitle>Journal of medicinal chemistry</jtitle><addtitle>J. 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ispartof | Journal of medicinal chemistry, 1974-08, Vol.17 (8), p.840-843 |
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language | eng |
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source | ACS Publications; MEDLINE |
subjects | Animals Antineoplastic Agents - chemical synthesis Antineoplastic Agents - therapeutic use Carcinoma Cell Line Fatty Acids, Unsaturated - chemical synthesis Fatty Acids, Unsaturated - therapeutic use Humans Lactones - chemical synthesis Lactones - therapeutic use Leukemia L1210 - drug therapy Mice Mouth Neoplasms Structure-Activity Relationship |
title | Synthesis of alkyl-substituted .alpha.,.beta.-unsaturated .gamma.-lactones as potential antitumor agents |
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