Reoviruslike Agent in Stools: Association with Infantile Diarrhea and Development of Serologic Tests

Reoviruslike particles were visualized by electron microscopy in stool filtrates prepared from stools of infants and young children with severe acute gastroenteritis. Patients who had such particles in their stools and whose paired acute and convalescent serums were tested developed an antibody resp...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Science (American Association for the Advancement of Science) 1974-09, Vol.185 (4156), p.1049-1053
Hauptverfasser: Kapikian, Albert Z., Kim, Hyun Wha, Wyatt, Richard G., Rodriguez, William J., Ross, Sydney, Cline, W. Lee, Parrott, Robert H., Chanock, Robert M.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1053
container_issue 4156
container_start_page 1049
container_title Science (American Association for the Advancement of Science)
container_volume 185
creator Kapikian, Albert Z.
Kim, Hyun Wha
Wyatt, Richard G.
Rodriguez, William J.
Ross, Sydney
Cline, W. Lee
Parrott, Robert H.
Chanock, Robert M.
description Reoviruslike particles were visualized by electron microscopy in stool filtrates prepared from stools of infants and young children with severe acute gastroenteritis. Patients who had such particles in their stools and whose paired acute and convalescent serums were tested developed an antibody response to the reoviruslike agent, which was measured by immune electron microscopy and by complement fixation. The reoviruslike agent was antigenically related to the epizootic diarrhea of infant mice virus and the Nebraska calf diarrhea virus.
doi_str_mv 10.1126/science.185.4156.1049
format Article
fullrecord <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_82463447</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>1738452</jstor_id><sourcerecordid>1738452</sourcerecordid><originalsourceid>FETCH-LOGICAL-c271t-c0f9dca6f6fbebfd1fb696fe4e1bea4415924688b931dc9d129ca38384e589523</originalsourceid><addsrcrecordid>eNpFkE9PAjEQxRujQUS_gSQ9eVtst92y9Ub8S0JiInhuut0pFJcttovGb28JRE9zeO_NvPkhNKRkRGkubqNx0BoY0bIYcVqIESVcnqA-JbLIZE7YKeoTwkRWknFxji5iXBOSNMl6qMcFKQhnfVS_gf9yYRcb9wF4soS2w67F8877Jt7hSYzeON053-Jv163wtLW67VwD-MHpEFagsW5r_ABf0PjtZh_3Fs8h-MYvncELiF28RGdWNxGujnOA3p8eF_cv2ez1eXo_mWUmH9MuM8TK2mhhha2gsjW1lZDCAgdagebpSZlzUZaVZLQ2sqa5NJqVrORQlLLI2QDdHPZug__cpctq46KBptEt-F1UZYozzsfJWByMJvgYA1i1DW6jw4-iRO3pqiNdleiqPV21p5tyw-OBXbWB-i91xJn064O-jp0P_0vHqWPq9wsSgILJ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>82463447</pqid></control><display><type>article</type><title>Reoviruslike Agent in Stools: Association with Infantile Diarrhea and Development of Serologic Tests</title><source>MEDLINE</source><source>JSTOR Archive Collection A-Z Listing</source><source>American Association for the Advancement of Science</source><creator>Kapikian, Albert Z. ; Kim, Hyun Wha ; Wyatt, Richard G. ; Rodriguez, William J. ; Ross, Sydney ; Cline, W. Lee ; Parrott, Robert H. ; Chanock, Robert M.</creator><creatorcontrib>Kapikian, Albert Z. ; Kim, Hyun Wha ; Wyatt, Richard G. ; Rodriguez, William J. ; Ross, Sydney ; Cline, W. Lee ; Parrott, Robert H. ; Chanock, Robert M.</creatorcontrib><description>Reoviruslike particles were visualized by electron microscopy in stool filtrates prepared from stools of infants and young children with severe acute gastroenteritis. Patients who had such particles in their stools and whose paired acute and convalescent serums were tested developed an antibody response to the reoviruslike agent, which was measured by immune electron microscopy and by complement fixation. The reoviruslike agent was antigenically related to the epizootic diarrhea of infant mice virus and the Nebraska calf diarrhea virus.</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.185.4156.1049</identifier><identifier>PMID: 4605043</identifier><language>eng</language><publisher>United States: American Association for the Advancement of Science</publisher><subject>Animals ; Antibodies ; Antigens ; Cattle ; Cattle Diseases - microbiology ; Child, Preschool ; Children ; Complement Fixation Tests ; Diarrhea ; Diarrhea - veterinary ; Diarrhea, Infantile - diagnosis ; Diarrhea, Infantile - microbiology ; Electron microscopy ; Feces - microbiology ; Gastroenteritis ; Gastroenteritis - diagnosis ; Gastroenteritis - microbiology ; Geologic tremors ; Humans ; Immunologic Techniques ; Infant ; Infants ; Mice ; Microscopy, Electron ; Reoviridae ; Reoviridae - immunology ; Reoviridae - isolation &amp; purification ; Rodent Diseases - microbiology ; Serologic Tests ; Viruses</subject><ispartof>Science (American Association for the Advancement of Science), 1974-09, Vol.185 (4156), p.1049-1053</ispartof><rights>Copyright 1974 American Association for the Advancement of Science</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c271t-c0f9dca6f6fbebfd1fb696fe4e1bea4415924688b931dc9d129ca38384e589523</citedby><cites>FETCH-LOGICAL-c271t-c0f9dca6f6fbebfd1fb696fe4e1bea4415924688b931dc9d129ca38384e589523</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/1738452$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/1738452$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,2884,2885,27924,27925,58017,58250</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4605043$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kapikian, Albert Z.</creatorcontrib><creatorcontrib>Kim, Hyun Wha</creatorcontrib><creatorcontrib>Wyatt, Richard G.</creatorcontrib><creatorcontrib>Rodriguez, William J.</creatorcontrib><creatorcontrib>Ross, Sydney</creatorcontrib><creatorcontrib>Cline, W. Lee</creatorcontrib><creatorcontrib>Parrott, Robert H.</creatorcontrib><creatorcontrib>Chanock, Robert M.</creatorcontrib><title>Reoviruslike Agent in Stools: Association with Infantile Diarrhea and Development of Serologic Tests</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>Reoviruslike particles were visualized by electron microscopy in stool filtrates prepared from stools of infants and young children with severe acute gastroenteritis. Patients who had such particles in their stools and whose paired acute and convalescent serums were tested developed an antibody response to the reoviruslike agent, which was measured by immune electron microscopy and by complement fixation. The reoviruslike agent was antigenically related to the epizootic diarrhea of infant mice virus and the Nebraska calf diarrhea virus.</description><subject>Animals</subject><subject>Antibodies</subject><subject>Antigens</subject><subject>Cattle</subject><subject>Cattle Diseases - microbiology</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Complement Fixation Tests</subject><subject>Diarrhea</subject><subject>Diarrhea - veterinary</subject><subject>Diarrhea, Infantile - diagnosis</subject><subject>Diarrhea, Infantile - microbiology</subject><subject>Electron microscopy</subject><subject>Feces - microbiology</subject><subject>Gastroenteritis</subject><subject>Gastroenteritis - diagnosis</subject><subject>Gastroenteritis - microbiology</subject><subject>Geologic tremors</subject><subject>Humans</subject><subject>Immunologic Techniques</subject><subject>Infant</subject><subject>Infants</subject><subject>Mice</subject><subject>Microscopy, Electron</subject><subject>Reoviridae</subject><subject>Reoviridae - immunology</subject><subject>Reoviridae - isolation &amp; purification</subject><subject>Rodent Diseases - microbiology</subject><subject>Serologic Tests</subject><subject>Viruses</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1974</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE9PAjEQxRujQUS_gSQ9eVtst92y9Ub8S0JiInhuut0pFJcttovGb28JRE9zeO_NvPkhNKRkRGkubqNx0BoY0bIYcVqIESVcnqA-JbLIZE7YKeoTwkRWknFxji5iXBOSNMl6qMcFKQhnfVS_gf9yYRcb9wF4soS2w67F8877Jt7hSYzeON053-Jv163wtLW67VwD-MHpEFagsW5r_ABf0PjtZh_3Fs8h-MYvncELiF28RGdWNxGujnOA3p8eF_cv2ez1eXo_mWUmH9MuM8TK2mhhha2gsjW1lZDCAgdagebpSZlzUZaVZLQ2sqa5NJqVrORQlLLI2QDdHPZug__cpctq46KBptEt-F1UZYozzsfJWByMJvgYA1i1DW6jw4-iRO3pqiNdleiqPV21p5tyw-OBXbWB-i91xJn064O-jp0P_0vHqWPq9wsSgILJ</recordid><startdate>19740920</startdate><enddate>19740920</enddate><creator>Kapikian, Albert Z.</creator><creator>Kim, Hyun Wha</creator><creator>Wyatt, Richard G.</creator><creator>Rodriguez, William J.</creator><creator>Ross, Sydney</creator><creator>Cline, W. Lee</creator><creator>Parrott, Robert H.</creator><creator>Chanock, Robert M.</creator><general>American Association for the Advancement of Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19740920</creationdate><title>Reoviruslike Agent in Stools: Association with Infantile Diarrhea and Development of Serologic Tests</title><author>Kapikian, Albert Z. ; Kim, Hyun Wha ; Wyatt, Richard G. ; Rodriguez, William J. ; Ross, Sydney ; Cline, W. Lee ; Parrott, Robert H. ; Chanock, Robert M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c271t-c0f9dca6f6fbebfd1fb696fe4e1bea4415924688b931dc9d129ca38384e589523</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1974</creationdate><topic>Animals</topic><topic>Antibodies</topic><topic>Antigens</topic><topic>Cattle</topic><topic>Cattle Diseases - microbiology</topic><topic>Child, Preschool</topic><topic>Children</topic><topic>Complement Fixation Tests</topic><topic>Diarrhea</topic><topic>Diarrhea - veterinary</topic><topic>Diarrhea, Infantile - diagnosis</topic><topic>Diarrhea, Infantile - microbiology</topic><topic>Electron microscopy</topic><topic>Feces - microbiology</topic><topic>Gastroenteritis</topic><topic>Gastroenteritis - diagnosis</topic><topic>Gastroenteritis - microbiology</topic><topic>Geologic tremors</topic><topic>Humans</topic><topic>Immunologic Techniques</topic><topic>Infant</topic><topic>Infants</topic><topic>Mice</topic><topic>Microscopy, Electron</topic><topic>Reoviridae</topic><topic>Reoviridae - immunology</topic><topic>Reoviridae - isolation &amp; purification</topic><topic>Rodent Diseases - microbiology</topic><topic>Serologic Tests</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kapikian, Albert Z.</creatorcontrib><creatorcontrib>Kim, Hyun Wha</creatorcontrib><creatorcontrib>Wyatt, Richard G.</creatorcontrib><creatorcontrib>Rodriguez, William J.</creatorcontrib><creatorcontrib>Ross, Sydney</creatorcontrib><creatorcontrib>Cline, W. Lee</creatorcontrib><creatorcontrib>Parrott, Robert H.</creatorcontrib><creatorcontrib>Chanock, Robert M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kapikian, Albert Z.</au><au>Kim, Hyun Wha</au><au>Wyatt, Richard G.</au><au>Rodriguez, William J.</au><au>Ross, Sydney</au><au>Cline, W. Lee</au><au>Parrott, Robert H.</au><au>Chanock, Robert M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reoviruslike Agent in Stools: Association with Infantile Diarrhea and Development of Serologic Tests</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1974-09-20</date><risdate>1974</risdate><volume>185</volume><issue>4156</issue><spage>1049</spage><epage>1053</epage><pages>1049-1053</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><abstract>Reoviruslike particles were visualized by electron microscopy in stool filtrates prepared from stools of infants and young children with severe acute gastroenteritis. Patients who had such particles in their stools and whose paired acute and convalescent serums were tested developed an antibody response to the reoviruslike agent, which was measured by immune electron microscopy and by complement fixation. The reoviruslike agent was antigenically related to the epizootic diarrhea of infant mice virus and the Nebraska calf diarrhea virus.</abstract><cop>United States</cop><pub>American Association for the Advancement of Science</pub><pmid>4605043</pmid><doi>10.1126/science.185.4156.1049</doi><tpages>5</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0036-8075
ispartof Science (American Association for the Advancement of Science), 1974-09, Vol.185 (4156), p.1049-1053
issn 0036-8075
1095-9203
language eng
recordid cdi_proquest_miscellaneous_82463447
source MEDLINE; JSTOR Archive Collection A-Z Listing; American Association for the Advancement of Science
subjects Animals
Antibodies
Antigens
Cattle
Cattle Diseases - microbiology
Child, Preschool
Children
Complement Fixation Tests
Diarrhea
Diarrhea - veterinary
Diarrhea, Infantile - diagnosis
Diarrhea, Infantile - microbiology
Electron microscopy
Feces - microbiology
Gastroenteritis
Gastroenteritis - diagnosis
Gastroenteritis - microbiology
Geologic tremors
Humans
Immunologic Techniques
Infant
Infants
Mice
Microscopy, Electron
Reoviridae
Reoviridae - immunology
Reoviridae - isolation & purification
Rodent Diseases - microbiology
Serologic Tests
Viruses
title Reoviruslike Agent in Stools: Association with Infantile Diarrhea and Development of Serologic Tests
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T16%3A25%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Reoviruslike%20Agent%20in%20Stools:%20Association%20with%20Infantile%20Diarrhea%20and%20Development%20of%20Serologic%20Tests&rft.jtitle=Science%20(American%20Association%20for%20the%20Advancement%20of%20Science)&rft.au=Kapikian,%20Albert%20Z.&rft.date=1974-09-20&rft.volume=185&rft.issue=4156&rft.spage=1049&rft.epage=1053&rft.pages=1049-1053&rft.issn=0036-8075&rft.eissn=1095-9203&rft_id=info:doi/10.1126/science.185.4156.1049&rft_dat=%3Cjstor_proqu%3E1738452%3C/jstor_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=82463447&rft_id=info:pmid/4605043&rft_jstor_id=1738452&rfr_iscdi=true