Reoviruslike Agent in Stools: Association with Infantile Diarrhea and Development of Serologic Tests
Reoviruslike particles were visualized by electron microscopy in stool filtrates prepared from stools of infants and young children with severe acute gastroenteritis. Patients who had such particles in their stools and whose paired acute and convalescent serums were tested developed an antibody resp...
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Veröffentlicht in: | Science (American Association for the Advancement of Science) 1974-09, Vol.185 (4156), p.1049-1053 |
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creator | Kapikian, Albert Z. Kim, Hyun Wha Wyatt, Richard G. Rodriguez, William J. Ross, Sydney Cline, W. Lee Parrott, Robert H. Chanock, Robert M. |
description | Reoviruslike particles were visualized by electron microscopy in stool filtrates prepared from stools of infants and young children with severe acute gastroenteritis. Patients who had such particles in their stools and whose paired acute and convalescent serums were tested developed an antibody response to the reoviruslike agent, which was measured by immune electron microscopy and by complement fixation. The reoviruslike agent was antigenically related to the epizootic diarrhea of infant mice virus and the Nebraska calf diarrhea virus. |
doi_str_mv | 10.1126/science.185.4156.1049 |
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The reoviruslike agent was antigenically related to the epizootic diarrhea of infant mice virus and the Nebraska calf diarrhea virus.</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.185.4156.1049</identifier><identifier>PMID: 4605043</identifier><language>eng</language><publisher>United States: American Association for the Advancement of Science</publisher><subject>Animals ; Antibodies ; Antigens ; Cattle ; Cattle Diseases - microbiology ; Child, Preschool ; Children ; Complement Fixation Tests ; Diarrhea ; Diarrhea - veterinary ; Diarrhea, Infantile - diagnosis ; Diarrhea, Infantile - microbiology ; Electron microscopy ; Feces - microbiology ; Gastroenteritis ; Gastroenteritis - diagnosis ; Gastroenteritis - microbiology ; Geologic tremors ; Humans ; Immunologic Techniques ; Infant ; Infants ; Mice ; Microscopy, Electron ; Reoviridae ; Reoviridae - immunology ; Reoviridae - isolation & purification ; Rodent Diseases - microbiology ; Serologic Tests ; Viruses</subject><ispartof>Science (American Association for the Advancement of Science), 1974-09, Vol.185 (4156), p.1049-1053</ispartof><rights>Copyright 1974 American Association for the Advancement of Science</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c271t-c0f9dca6f6fbebfd1fb696fe4e1bea4415924688b931dc9d129ca38384e589523</citedby><cites>FETCH-LOGICAL-c271t-c0f9dca6f6fbebfd1fb696fe4e1bea4415924688b931dc9d129ca38384e589523</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/1738452$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/1738452$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,2884,2885,27924,27925,58017,58250</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4605043$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kapikian, Albert Z.</creatorcontrib><creatorcontrib>Kim, Hyun Wha</creatorcontrib><creatorcontrib>Wyatt, Richard G.</creatorcontrib><creatorcontrib>Rodriguez, William J.</creatorcontrib><creatorcontrib>Ross, Sydney</creatorcontrib><creatorcontrib>Cline, W. Lee</creatorcontrib><creatorcontrib>Parrott, Robert H.</creatorcontrib><creatorcontrib>Chanock, Robert M.</creatorcontrib><title>Reoviruslike Agent in Stools: Association with Infantile Diarrhea and Development of Serologic Tests</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>Reoviruslike particles were visualized by electron microscopy in stool filtrates prepared from stools of infants and young children with severe acute gastroenteritis. Patients who had such particles in their stools and whose paired acute and convalescent serums were tested developed an antibody response to the reoviruslike agent, which was measured by immune electron microscopy and by complement fixation. The reoviruslike agent was antigenically related to the epizootic diarrhea of infant mice virus and the Nebraska calf diarrhea virus.</description><subject>Animals</subject><subject>Antibodies</subject><subject>Antigens</subject><subject>Cattle</subject><subject>Cattle Diseases - microbiology</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Complement Fixation Tests</subject><subject>Diarrhea</subject><subject>Diarrhea - veterinary</subject><subject>Diarrhea, Infantile - diagnosis</subject><subject>Diarrhea, Infantile - microbiology</subject><subject>Electron microscopy</subject><subject>Feces - microbiology</subject><subject>Gastroenteritis</subject><subject>Gastroenteritis - diagnosis</subject><subject>Gastroenteritis - microbiology</subject><subject>Geologic tremors</subject><subject>Humans</subject><subject>Immunologic Techniques</subject><subject>Infant</subject><subject>Infants</subject><subject>Mice</subject><subject>Microscopy, Electron</subject><subject>Reoviridae</subject><subject>Reoviridae - immunology</subject><subject>Reoviridae - isolation & purification</subject><subject>Rodent Diseases - microbiology</subject><subject>Serologic Tests</subject><subject>Viruses</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1974</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE9PAjEQxRujQUS_gSQ9eVtst92y9Ub8S0JiInhuut0pFJcttovGb28JRE9zeO_NvPkhNKRkRGkubqNx0BoY0bIYcVqIESVcnqA-JbLIZE7YKeoTwkRWknFxji5iXBOSNMl6qMcFKQhnfVS_gf9yYRcb9wF4soS2w67F8877Jt7hSYzeON053-Jv163wtLW67VwD-MHpEFagsW5r_ABf0PjtZh_3Fs8h-MYvncELiF28RGdWNxGujnOA3p8eF_cv2ez1eXo_mWUmH9MuM8TK2mhhha2gsjW1lZDCAgdagebpSZlzUZaVZLQ2sqa5NJqVrORQlLLI2QDdHPZug__cpctq46KBptEt-F1UZYozzsfJWByMJvgYA1i1DW6jw4-iRO3pqiNdleiqPV21p5tyw-OBXbWB-i91xJn064O-jp0P_0vHqWPq9wsSgILJ</recordid><startdate>19740920</startdate><enddate>19740920</enddate><creator>Kapikian, Albert Z.</creator><creator>Kim, Hyun Wha</creator><creator>Wyatt, Richard G.</creator><creator>Rodriguez, William J.</creator><creator>Ross, Sydney</creator><creator>Cline, W. Lee</creator><creator>Parrott, Robert H.</creator><creator>Chanock, Robert M.</creator><general>American Association for the Advancement of Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19740920</creationdate><title>Reoviruslike Agent in Stools: Association with Infantile Diarrhea and Development of Serologic Tests</title><author>Kapikian, Albert Z. ; Kim, Hyun Wha ; Wyatt, Richard G. ; Rodriguez, William J. ; Ross, Sydney ; Cline, W. Lee ; Parrott, Robert H. ; Chanock, Robert M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c271t-c0f9dca6f6fbebfd1fb696fe4e1bea4415924688b931dc9d129ca38384e589523</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1974</creationdate><topic>Animals</topic><topic>Antibodies</topic><topic>Antigens</topic><topic>Cattle</topic><topic>Cattle Diseases - microbiology</topic><topic>Child, Preschool</topic><topic>Children</topic><topic>Complement Fixation Tests</topic><topic>Diarrhea</topic><topic>Diarrhea - veterinary</topic><topic>Diarrhea, Infantile - diagnosis</topic><topic>Diarrhea, Infantile - microbiology</topic><topic>Electron microscopy</topic><topic>Feces - microbiology</topic><topic>Gastroenteritis</topic><topic>Gastroenteritis - diagnosis</topic><topic>Gastroenteritis - microbiology</topic><topic>Geologic tremors</topic><topic>Humans</topic><topic>Immunologic Techniques</topic><topic>Infant</topic><topic>Infants</topic><topic>Mice</topic><topic>Microscopy, Electron</topic><topic>Reoviridae</topic><topic>Reoviridae - immunology</topic><topic>Reoviridae - isolation & purification</topic><topic>Rodent Diseases - microbiology</topic><topic>Serologic Tests</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kapikian, Albert Z.</creatorcontrib><creatorcontrib>Kim, Hyun Wha</creatorcontrib><creatorcontrib>Wyatt, Richard G.</creatorcontrib><creatorcontrib>Rodriguez, William J.</creatorcontrib><creatorcontrib>Ross, Sydney</creatorcontrib><creatorcontrib>Cline, W. 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Lee</au><au>Parrott, Robert H.</au><au>Chanock, Robert M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reoviruslike Agent in Stools: Association with Infantile Diarrhea and Development of Serologic Tests</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1974-09-20</date><risdate>1974</risdate><volume>185</volume><issue>4156</issue><spage>1049</spage><epage>1053</epage><pages>1049-1053</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><abstract>Reoviruslike particles were visualized by electron microscopy in stool filtrates prepared from stools of infants and young children with severe acute gastroenteritis. Patients who had such particles in their stools and whose paired acute and convalescent serums were tested developed an antibody response to the reoviruslike agent, which was measured by immune electron microscopy and by complement fixation. The reoviruslike agent was antigenically related to the epizootic diarrhea of infant mice virus and the Nebraska calf diarrhea virus.</abstract><cop>United States</cop><pub>American Association for the Advancement of Science</pub><pmid>4605043</pmid><doi>10.1126/science.185.4156.1049</doi><tpages>5</tpages></addata></record> |
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source | MEDLINE; JSTOR Archive Collection A-Z Listing; American Association for the Advancement of Science |
subjects | Animals Antibodies Antigens Cattle Cattle Diseases - microbiology Child, Preschool Children Complement Fixation Tests Diarrhea Diarrhea - veterinary Diarrhea, Infantile - diagnosis Diarrhea, Infantile - microbiology Electron microscopy Feces - microbiology Gastroenteritis Gastroenteritis - diagnosis Gastroenteritis - microbiology Geologic tremors Humans Immunologic Techniques Infant Infants Mice Microscopy, Electron Reoviridae Reoviridae - immunology Reoviridae - isolation & purification Rodent Diseases - microbiology Serologic Tests Viruses |
title | Reoviruslike Agent in Stools: Association with Infantile Diarrhea and Development of Serologic Tests |
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