Correlation between brain adenyl cyclase activity and spontaneous motor activity in rats after chronic reserpine treatment

Reserpine (0.5 mg/kg) was administered daily to rats for a period of 8–12 days. Motor activity was measured 23–24 h after each injection. Twenty-four hours subsequent to the last reserpine injection, animals were sacrificed for determination of whole brain catecholamine concentration and adenyl cycl...

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Veröffentlicht in:	Brain research 1974-03, Vol.68 (2), p.227-234
Hauptverfasser:	Williams, Betty J., Pirch, James H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Adenylyl Cyclases - metabolism Animals Brain - drug effects Brain - enzymology Brain Chemistry Carbon Radioisotopes Catecholamines - analysis Cyclic AMP - biosynthesis Female Humans Hyperkinesis Injections, Intraperitoneal Motor Activity - drug effects Norepinephrine - analysis Rats Reserpine - administration & dosage Reserpine - pharmacology Stimulation, Chemical Time Factors
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