Determination of amniotic fluid phospholipids for the diagnosis of fetal maturation
In 111 patients, the L/S ratio, the concentration of phospholipids, lecithin, phosphate in total lipids, creatinine, and the foam test were determined at various periods of gestation by amniocentesis. Surface tension of amniotic fluid was measured by two different techniques (the angle of intersecti...
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Veröffentlicht in: | American journal of obstetrics and gynecology 1974-05, Vol.119 (1), p.104-110 |
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creator | Nakamura, Junichi Roux, Jacques F. |
description | In 111 patients, the L/S ratio, the concentration of phospholipids, lecithin, phosphate in total lipids, creatinine, and the foam test were determined at various periods of gestation by amniocentesis. Surface tension of amniotic fluid was measured by two different techniques (the angle of intersection and the bubble disappearance rate). Each test, with the exception of the angle of intersection and the concentration of phosphate in total lipids, correlates significantly with gestational age and with the L/S ratio of Gluck and Kulovich. The S.D. of each test is large. From the data it is concluded that the determination of amniotic fluid creatinine concentration and the use of the foam test provide fast, cheap, and reliable information when the tests are positive for maturation. If the amniotic fluid tests are in the immature range, amniocentesis should be repeated. |
doi_str_mv | 10.1016/0002-9378(74)90323-8 |
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Surface tension of amniotic fluid was measured by two different techniques (the angle of intersection and the bubble disappearance rate). Each test, with the exception of the angle of intersection and the concentration of phosphate in total lipids, correlates significantly with gestational age and with the L/S ratio of Gluck and Kulovich. The S.D. of each test is large. From the data it is concluded that the determination of amniotic fluid creatinine concentration and the use of the foam test provide fast, cheap, and reliable information when the tests are positive for maturation. If the amniotic fluid tests are in the immature range, amniocentesis should be repeated.</description><identifier>ISSN: 0002-9378</identifier><identifier>EISSN: 1097-6868</identifier><identifier>DOI: 10.1016/0002-9378(74)90323-8</identifier><identifier>PMID: 4820904</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Acetone ; Amniocentesis ; Amniotic Fluid - analysis ; Chemical Precipitation ; Creatinine - analysis ; Embryonic and Fetal Development ; Female ; Gestational Age ; Humans ; Lung - embryology ; Phosphates - analysis ; Phosphatidylcholines - analysis ; Phospholipids - analysis ; Pregnancy ; Sphingomyelins - analysis ; Surface Tension</subject><ispartof>American journal of obstetrics and gynecology, 1974-05, Vol.119 (1), p.104-110</ispartof><rights>1974</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-ade414d0cca1ef417ff090b0ed0fe54f3ac8daa35cab5882ad2e3cca99e1f5483</citedby><cites>FETCH-LOGICAL-c357t-ade414d0cca1ef417ff090b0ed0fe54f3ac8daa35cab5882ad2e3cca99e1f5483</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0002-9378(74)90323-8$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3541,27915,27916,45986</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4820904$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nakamura, Junichi</creatorcontrib><creatorcontrib>Roux, Jacques F.</creatorcontrib><title>Determination of amniotic fluid phospholipids for the diagnosis of fetal maturation</title><title>American journal of obstetrics and gynecology</title><addtitle>Am J Obstet Gynecol</addtitle><description>In 111 patients, the L/S ratio, the concentration of phospholipids, lecithin, phosphate in total lipids, creatinine, and the foam test were determined at various periods of gestation by amniocentesis. Surface tension of amniotic fluid was measured by two different techniques (the angle of intersection and the bubble disappearance rate). Each test, with the exception of the angle of intersection and the concentration of phosphate in total lipids, correlates significantly with gestational age and with the L/S ratio of Gluck and Kulovich. The S.D. of each test is large. From the data it is concluded that the determination of amniotic fluid creatinine concentration and the use of the foam test provide fast, cheap, and reliable information when the tests are positive for maturation. If the amniotic fluid tests are in the immature range, amniocentesis should be repeated.</description><subject>Acetone</subject><subject>Amniocentesis</subject><subject>Amniotic Fluid - analysis</subject><subject>Chemical Precipitation</subject><subject>Creatinine - analysis</subject><subject>Embryonic and Fetal Development</subject><subject>Female</subject><subject>Gestational Age</subject><subject>Humans</subject><subject>Lung - embryology</subject><subject>Phosphates - analysis</subject><subject>Phosphatidylcholines - analysis</subject><subject>Phospholipids - analysis</subject><subject>Pregnancy</subject><subject>Sphingomyelins - analysis</subject><subject>Surface Tension</subject><issn>0002-9378</issn><issn>1097-6868</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1974</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LxDAQhoMo67r6DxR6Ej1UkybdJhdB1k9Y8KCeQzaZuJG2qUkq-O9tdxePHoZhmHfemXkQOiX4imAyv8YYF7mgFb-o2KXAtKA530NTgkWVz_mc76Ppn-QQHcX4OZaFKCZowniBBWZT9HoHCULjWpWcbzNvM9W0zienM1v3zmTd2schatc5EzPrQ5bWkBmnPlofXRwnLCRVZ41Kfdi4HKMDq-oIJ7s8Q-8P92-Lp3z58vi8uF3mmpZVypUBRpjBWisClpHK2uGmFQaDLZTMUqW5UYqWWq1KzgtlCqCDWAggtmScztD51rcL_quHmGTjooa6Vi34PkpeUEoIE4OQbYU6-BgDWNkF16jwIwmWI0s5kpEjKFkxuWEpR_-znX-_asD8De3gDf2bbR-GJ78dBBm1g1aDcQF0ksa7_xf8AlmvhXc</recordid><startdate>19740501</startdate><enddate>19740501</enddate><creator>Nakamura, Junichi</creator><creator>Roux, Jacques F.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19740501</creationdate><title>Determination of amniotic fluid phospholipids for the diagnosis of fetal maturation</title><author>Nakamura, Junichi ; Roux, Jacques F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-ade414d0cca1ef417ff090b0ed0fe54f3ac8daa35cab5882ad2e3cca99e1f5483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1974</creationdate><topic>Acetone</topic><topic>Amniocentesis</topic><topic>Amniotic Fluid - analysis</topic><topic>Chemical Precipitation</topic><topic>Creatinine - analysis</topic><topic>Embryonic and Fetal Development</topic><topic>Female</topic><topic>Gestational Age</topic><topic>Humans</topic><topic>Lung - embryology</topic><topic>Phosphates - analysis</topic><topic>Phosphatidylcholines - analysis</topic><topic>Phospholipids - analysis</topic><topic>Pregnancy</topic><topic>Sphingomyelins - analysis</topic><topic>Surface Tension</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nakamura, Junichi</creatorcontrib><creatorcontrib>Roux, Jacques F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of obstetrics and gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nakamura, Junichi</au><au>Roux, Jacques F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Determination of amniotic fluid phospholipids for the diagnosis of fetal maturation</atitle><jtitle>American journal of obstetrics and gynecology</jtitle><addtitle>Am J Obstet Gynecol</addtitle><date>1974-05-01</date><risdate>1974</risdate><volume>119</volume><issue>1</issue><spage>104</spage><epage>110</epage><pages>104-110</pages><issn>0002-9378</issn><eissn>1097-6868</eissn><abstract>In 111 patients, the L/S ratio, the concentration of phospholipids, lecithin, phosphate in total lipids, creatinine, and the foam test were determined at various periods of gestation by amniocentesis. Surface tension of amniotic fluid was measured by two different techniques (the angle of intersection and the bubble disappearance rate). Each test, with the exception of the angle of intersection and the concentration of phosphate in total lipids, correlates significantly with gestational age and with the L/S ratio of Gluck and Kulovich. The S.D. of each test is large. From the data it is concluded that the determination of amniotic fluid creatinine concentration and the use of the foam test provide fast, cheap, and reliable information when the tests are positive for maturation. If the amniotic fluid tests are in the immature range, amniocentesis should be repeated.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>4820904</pmid><doi>10.1016/0002-9378(74)90323-8</doi><tpages>7</tpages></addata></record> |
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source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Acetone Amniocentesis Amniotic Fluid - analysis Chemical Precipitation Creatinine - analysis Embryonic and Fetal Development Female Gestational Age Humans Lung - embryology Phosphates - analysis Phosphatidylcholines - analysis Phospholipids - analysis Pregnancy Sphingomyelins - analysis Surface Tension |
title | Determination of amniotic fluid phospholipids for the diagnosis of fetal maturation |
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