Determination of amniotic fluid phospholipids for the diagnosis of fetal maturation

In 111 patients, the L/S ratio, the concentration of phospholipids, lecithin, phosphate in total lipids, creatinine, and the foam test were determined at various periods of gestation by amniocentesis. Surface tension of amniotic fluid was measured by two different techniques (the angle of intersecti...

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Veröffentlicht in:American journal of obstetrics and gynecology 1974-05, Vol.119 (1), p.104-110
Hauptverfasser: Nakamura, Junichi, Roux, Jacques F.
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container_title American journal of obstetrics and gynecology
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creator Nakamura, Junichi
Roux, Jacques F.
description In 111 patients, the L/S ratio, the concentration of phospholipids, lecithin, phosphate in total lipids, creatinine, and the foam test were determined at various periods of gestation by amniocentesis. Surface tension of amniotic fluid was measured by two different techniques (the angle of intersection and the bubble disappearance rate). Each test, with the exception of the angle of intersection and the concentration of phosphate in total lipids, correlates significantly with gestational age and with the L/S ratio of Gluck and Kulovich. The S.D. of each test is large. From the data it is concluded that the determination of amniotic fluid creatinine concentration and the use of the foam test provide fast, cheap, and reliable information when the tests are positive for maturation. If the amniotic fluid tests are in the immature range, amniocentesis should be repeated.
doi_str_mv 10.1016/0002-9378(74)90323-8
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subjects Acetone
Amniocentesis
Amniotic Fluid - analysis
Chemical Precipitation
Creatinine - analysis
Embryonic and Fetal Development
Female
Gestational Age
Humans
Lung - embryology
Phosphates - analysis
Phosphatidylcholines - analysis
Phospholipids - analysis
Pregnancy
Sphingomyelins - analysis
Surface Tension
title Determination of amniotic fluid phospholipids for the diagnosis of fetal maturation
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