The Utilization of Properdin in the Alternate Pathway of Complement Activation: Isolation of Properdin Convertase

Normal human serum contains an α-globulin, designated properdin convertase, which after activation by zymosan will interact with native properdin to generate a C3 reactive enzyme. The activation of properdin convertase as well as its interaction with properdin after activation requires no additional...

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Veröffentlicht in:	The Journal of immunology (1950) 1974-01, Vol.112 (1), p.56-62
Hauptverfasser:	Stitzel, Ann E, Spitzer, Roger E
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha-Globulins - isolation & purification Animals Complement System Proteins - isolation & purification Complement System Proteins - metabolism Electrophoresis, Polyacrylamide Gel Enzyme Activation Erythrocytes - immunology Goats - immunology Guinea Pigs - immunology Hemolysis Humans Immune Sera Immunoelectrophoresis Properdin - isolation & purification Properdin - metabolism Zymosan
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