A Sequence Restriction in the Variable Region of Immunoglobulin Light Chains from Sharks, Birds, and Mammals

A relatively conserved pentapeptide sequence is present in the variable region of normal immunoglobulin λ- and κ-chains from animals as diverse as sharks, birds, and mammals. This same conserved sequence is also present in most myeloma light chains from dog, mouse, and man. The conservation of this...

Ausführliche Beschreibung