Impact of Chronic Pre-Treatment of Statins on the Level of Systemic Inflammation and Myocardial Perfusion in Patients Undergoing Primary Angioplasty

Statins have many favorable pleiotropic effects beyond their lipid-lowering properties. The aim of this study was to evaluate the impact of long-term statin pretreatment on the level of systemic inflammation and myocardial perfusion in patients with acute myocardial infarctions. This was a retrospec...

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Veröffentlicht in:	The American journal of cardiology 2011-01, Vol.107 (2), p.179-185
Hauptverfasser:	Oduncu, Vecih, MD, Tanalp, Ali Cevat, MD, Erkol, Ayhan, MD, Sırma, Dicle, MD, Dündar, Cihan, MD, Akgün, Taylan, MD, Türkyılmaz, Erdem, MD, Kılıçgedik, Alev, MD, Gözübüyük, Gökhan, MD, Tigen, Kürşat, MD, Izgi, Akın, MD, Kırma, Cevat, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Angioplasty Angioplasty, Balloon, Coronary Biological and medical sciences C-Reactive Protein - metabolism Cardiology Cardiology. Vascular system Cardiovascular Cardiovascular disease Coronary Angiography Coronary Circulation - drug effects Diseases of the cardiovascular system Electrocardiography Female Follow-Up Studies Heart attacks Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Inflammation - blood Lipids Male Medical sciences Medical treatment Middle Aged Myocardial Ischemia - blood Myocardial Ischemia - drug therapy Myocardial Ischemia - physiopathology Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Retrospective Studies Statins Time Factors Treatment Outcome
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Beschreibung
Zusammenfassung:	Statins have many favorable pleiotropic effects beyond their lipid-lowering properties. The aim of this study was to evaluate the impact of long-term statin pretreatment on the level of systemic inflammation and myocardial perfusion in patients with acute myocardial infarctions. This was a retrospective study of 1,617 patients with acute ST-segment elevation myocardial infarctions who underwent primary percutaneous coronary intervention
ISSN:	0002-9149 1879-1913
DOI:	10.1016/j.amjcard.2010.09.008