Lowering the Triglyceride/High-Density Lipoprotein Cholesterol Ratio Is Associated With the Beneficial Impact of Pioglitazone on Progression of Coronary Atherosclerosis in Diabetic Patients: Insights From the PERISCOPE (Pioglitazone Effect on Regression of Intravascular Sonographic Coronary Obstruction Prospective Evaluation) Study

The purpose of this study was to determine the factors associated with the favorable effect of pioglitazone on atheroma progression. Diabetes mellitus is associated with accelerated coronary atheroma progression. Pioglitazone slowed progression compared with glimepiride in this population. In all, 3...

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Veröffentlicht in:	Journal of the American College of Cardiology 2011-01, Vol.57 (2), p.153-159
Hauptverfasser:	NICHOLLS, Stephen J, MURAT TUZCU, E, WOLSKI, Kathy, BAYTURAN, Ozgur, LAVOIE, Andrea, UNO, Kiyoko, KUPFER, Stuart, PEREZ, Alfonso, NESTO, Richard, NISSEN, Steven E
Format:	Artikel
Sprache:	eng
Schlagworte:	Atherosclerosis Atherosclerosis (general aspects, experimental research) Atherosclerosis - blood Atherosclerosis - complications Atherosclerosis - diagnostic imaging Biological and medical sciences Blood and lymphatic vessels Cardiology Cardiology. Vascular system Cardiovascular disease Cholesterol Cholesterol, HDL - blood Cholesterol, HDL - drug effects Coronary Artery Disease - blood Coronary Artery Disease - complications Coronary Artery Disease - diagnostic imaging Coronary heart disease Coronary Stenosis - blood Coronary Stenosis - complications Coronary Stenosis - diagnostic imaging Diabetes Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - drug therapy Diabetes. Impaired glucose tolerance Disease Progression Double-Blind Method Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Follow-Up Studies Glucose Heart Heart attacks Humans Hypertension Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - therapeutic use Lipoproteins Medical sciences Normal distribution Prognosis Prospective Studies Thiazolidinediones - administration & dosage Thiazolidinediones - therapeutic use Triglycerides Triglycerides - blood Ultrasonic imaging Ultrasonography, Interventional - methods
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