Ultrastructural alterations induced by Δ(24(25))-sterol methyltransferase inhibitors on Trichomonas vaginalis

Trichomonas vaginalis is an important human parasite that causes trichomoniasis, a cosmopolitan sexually transmitted disease. Currently, the treatment of choice for T. vaginalis infections is metronidazole. The increase in metronidazole-resistant parasites and undesirable side effects of this drug m...

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Veröffentlicht in:	FEMS microbiology letters 2011-02, Vol.315 (1), p.72-78
Hauptverfasser:	Rosa, Ivone de Andrade, Rocha, Débora Afonso Silva, de Souza, Wanderley, Urbina, Julio A, Benchimol, Marlene
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antitrichomonal Agents - pharmacology Cell Line Cell Proliferation - drug effects Cholestanol - analogs & derivatives Cholestanol - pharmacology Dogs Enzyme Inhibitors - pharmacology Lanosterol - analogs & derivatives Lanosterol - pharmacology Methyltransferases - antagonists & inhibitors Microscopy, Electron, Scanning Microscopy, Electron, Transmission Parasitic Sensitivity Tests Toxicity Tests Trichomonas vaginalis - drug effects Trichomonas vaginalis - enzymology Trichomonas vaginalis - growth & development Trichomonas vaginalis - ultrastructure
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