Influence of Pluronic® F68 on Ceftazidime Biological Activity in Parenteral Solutions

β-Lactam antimicrobials are known to have a low concentration/therapeutic response. However, extending the period in which β-lactam are free in the plasma does directly influence therapeutic outcomes. The objective of this study was to evaluate the influence of Pluronic® F68 on the antimicrobial act...

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Veröffentlicht in:	Journal of pharmaceutical sciences 2011-02, Vol.100 (2), p.715-720
Hauptverfasser:	Dos Santos, Carolina Alves, Ribeiro, Gabriel Borghesan, Knirsch, Marcos Camargo, Junior, Adalberto Pessoa, Vessoni Penna, Thereza Christina
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminophylline - pharmacology Anti-Bacterial Agents - pharmacology Biological and medical sciences Bronchodilator Agents - pharmacology Ceftazidime - pharmacology chemical stability Drug Interactions Escherichia coli - drug effects Escherichia coli Infections - drug therapy Excipients - pharmacology General pharmacology Humans injectables Injections Medical sciences Microbial Sensitivity Tests nanotechnology Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Poloxamer - pharmacology polymers Pseudomonas aeruginosa - drug effects Pseudomonas Infections - drug therapy
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