Correlating Mechanical Properties with Aggregation Processes in Electrochemically Fabricated Collagen Membranes
We show that mechanical stiffness is a useful metric for characterizing complex collagen assemblies, providing insight about aggregation products and pathways in collagen-based materials. This study focuses on mechanically robust collagenous membranes produced by an electrochemical synthesis process...
Gespeichert in:
| Veröffentlicht in: | Biomacromolecules 2009-07, Vol.10 (7), p.1970-1975 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1975 |
|---|---|
| container_issue | 7 |
| container_start_page | 1970 |
| container_title | Biomacromolecules |
| container_volume | 10 |
| creator | Kumar, M. Ramesh Merschrod S, Erika F Poduska, Kristin M |
| description | We show that mechanical stiffness is a useful metric for characterizing complex collagen assemblies, providing insight about aggregation products and pathways in collagen-based materials. This study focuses on mechanically robust collagenous membranes produced by an electrochemical synthesis process. Changing the duration of the applied electric field, or adjusting the electrolyte composition (by adding Ca2+, K+, or Na+ or by changing pH), produces membranes with a range of Young’s moduli as determined from force-displacement measurements with an atomic force microscope. The structural organization, characterized by UV−visible spectroscopy, Raman spectroscopy, optical microscopy, and atomic force microscopy, correlates with the mechanical stiffness. These data provide insights into the relative importance of different aggregation pathways enabled by our multiparameter electrochemically induced collagen assembly process. |
| doi_str_mv | 10.1021/bm900379g |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_822555761</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>822555761</sourcerecordid><originalsourceid>FETCH-LOGICAL-a411t-b999748acbc3eb5f204fbd69c819ee840b7286299b615f7db1b3dc71f675f9cd3</originalsourceid><addsrcrecordid>eNqFkU1LxDAQhoMo7vpx8A9ILyIeqkmaj-YoxVVB0YOeS5JOu5W2WZMW2X9vVhe9CJ5mmHnmneEdhE4IviSYkivTK4wzqZodNCecipQJTHe_cp5KqeQMHYTwhjFWGeP7aEYU4xkRfI5c4byHTo_t0CSPYJd6aK3ukmfvVuDHFkLy0Y7L5LppPDQRc8OmZyGE2GqH5KYDO8bCEvrNYLdOFtr4mI5QJYXrOt3AEJV74_UA4Qjt1boLcLyNh-h1cfNS3KUPT7f3xfVDqhkhY2qUUpLl2hqbgeE1xaw2lVA2JwogZ9hImguqlBGE17IyxGSVlaQWktfKVtkhOv_WXXn3PkEYy74NFuI5A7gplDmlnHMpyL-k5IyzXAgcyYtv0noXgoe6XPm2135dElxuHlH-PCKyp1vVyfRQ_ZJb5yNwtgV0iL7V0R3bhh-OUiyUJPSX0zaUb27yQ7Ttj4WfUf6dsw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>754548660</pqid></control><display><type>article</type><title>Correlating Mechanical Properties with Aggregation Processes in Electrochemically Fabricated Collagen Membranes</title><source>MEDLINE</source><source>ACS Publications</source><creator>Kumar, M. Ramesh ; Merschrod S, Erika F ; Poduska, Kristin M</creator><creatorcontrib>Kumar, M. Ramesh ; Merschrod S, Erika F ; Poduska, Kristin M</creatorcontrib><description>We show that mechanical stiffness is a useful metric for characterizing complex collagen assemblies, providing insight about aggregation products and pathways in collagen-based materials. This study focuses on mechanically robust collagenous membranes produced by an electrochemical synthesis process. Changing the duration of the applied electric field, or adjusting the electrolyte composition (by adding Ca2+, K+, or Na+ or by changing pH), produces membranes with a range of Young’s moduli as determined from force-displacement measurements with an atomic force microscope. The structural organization, characterized by UV−visible spectroscopy, Raman spectroscopy, optical microscopy, and atomic force microscopy, correlates with the mechanical stiffness. These data provide insights into the relative importance of different aggregation pathways enabled by our multiparameter electrochemically induced collagen assembly process.</description><identifier>ISSN: 1525-7797</identifier><identifier>EISSN: 1526-4602</identifier><identifier>DOI: 10.1021/bm900379g</identifier><identifier>PMID: 19453165</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Applied sciences ; Collagen - chemistry ; Electrochemical Techniques ; Exact sciences and technology ; Exchange resins and membranes ; Forms of application and semi-finished materials ; Mechanical Phenomena ; Membranes, Artificial ; Microscopy, Atomic Force ; Natural polymers ; Physicochemistry of polymers ; Pliability ; Polymer industry, paints, wood ; Proteins ; Spectrum Analysis ; Technology of polymers</subject><ispartof>Biomacromolecules, 2009-07, Vol.10 (7), p.1970-1975</ispartof><rights>Copyright © 2009 American Chemical Society</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a411t-b999748acbc3eb5f204fbd69c819ee840b7286299b615f7db1b3dc71f675f9cd3</citedby><cites>FETCH-LOGICAL-a411t-b999748acbc3eb5f204fbd69c819ee840b7286299b615f7db1b3dc71f675f9cd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/bm900379g$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/bm900379g$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,780,784,2764,27075,27923,27924,56737,56787</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22069712$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19453165$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kumar, M. Ramesh</creatorcontrib><creatorcontrib>Merschrod S, Erika F</creatorcontrib><creatorcontrib>Poduska, Kristin M</creatorcontrib><title>Correlating Mechanical Properties with Aggregation Processes in Electrochemically Fabricated Collagen Membranes</title><title>Biomacromolecules</title><addtitle>Biomacromolecules</addtitle><description>We show that mechanical stiffness is a useful metric for characterizing complex collagen assemblies, providing insight about aggregation products and pathways in collagen-based materials. This study focuses on mechanically robust collagenous membranes produced by an electrochemical synthesis process. Changing the duration of the applied electric field, or adjusting the electrolyte composition (by adding Ca2+, K+, or Na+ or by changing pH), produces membranes with a range of Young’s moduli as determined from force-displacement measurements with an atomic force microscope. The structural organization, characterized by UV−visible spectroscopy, Raman spectroscopy, optical microscopy, and atomic force microscopy, correlates with the mechanical stiffness. These data provide insights into the relative importance of different aggregation pathways enabled by our multiparameter electrochemically induced collagen assembly process.</description><subject>Applied sciences</subject><subject>Collagen - chemistry</subject><subject>Electrochemical Techniques</subject><subject>Exact sciences and technology</subject><subject>Exchange resins and membranes</subject><subject>Forms of application and semi-finished materials</subject><subject>Mechanical Phenomena</subject><subject>Membranes, Artificial</subject><subject>Microscopy, Atomic Force</subject><subject>Natural polymers</subject><subject>Physicochemistry of polymers</subject><subject>Pliability</subject><subject>Polymer industry, paints, wood</subject><subject>Proteins</subject><subject>Spectrum Analysis</subject><subject>Technology of polymers</subject><issn>1525-7797</issn><issn>1526-4602</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1LxDAQhoMo7vpx8A9ILyIeqkmaj-YoxVVB0YOeS5JOu5W2WZMW2X9vVhe9CJ5mmHnmneEdhE4IviSYkivTK4wzqZodNCecipQJTHe_cp5KqeQMHYTwhjFWGeP7aEYU4xkRfI5c4byHTo_t0CSPYJd6aK3ukmfvVuDHFkLy0Y7L5LppPDQRc8OmZyGE2GqH5KYDO8bCEvrNYLdOFtr4mI5QJYXrOt3AEJV74_UA4Qjt1boLcLyNh-h1cfNS3KUPT7f3xfVDqhkhY2qUUpLl2hqbgeE1xaw2lVA2JwogZ9hImguqlBGE17IyxGSVlaQWktfKVtkhOv_WXXn3PkEYy74NFuI5A7gplDmlnHMpyL-k5IyzXAgcyYtv0noXgoe6XPm2135dElxuHlH-PCKyp1vVyfRQ_ZJb5yNwtgV0iL7V0R3bhh-OUiyUJPSX0zaUb27yQ7Ttj4WfUf6dsw</recordid><startdate>20090713</startdate><enddate>20090713</enddate><creator>Kumar, M. Ramesh</creator><creator>Merschrod S, Erika F</creator><creator>Poduska, Kristin M</creator><general>American Chemical Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20090713</creationdate><title>Correlating Mechanical Properties with Aggregation Processes in Electrochemically Fabricated Collagen Membranes</title><author>Kumar, M. Ramesh ; Merschrod S, Erika F ; Poduska, Kristin M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a411t-b999748acbc3eb5f204fbd69c819ee840b7286299b615f7db1b3dc71f675f9cd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Applied sciences</topic><topic>Collagen - chemistry</topic><topic>Electrochemical Techniques</topic><topic>Exact sciences and technology</topic><topic>Exchange resins and membranes</topic><topic>Forms of application and semi-finished materials</topic><topic>Mechanical Phenomena</topic><topic>Membranes, Artificial</topic><topic>Microscopy, Atomic Force</topic><topic>Natural polymers</topic><topic>Physicochemistry of polymers</topic><topic>Pliability</topic><topic>Polymer industry, paints, wood</topic><topic>Proteins</topic><topic>Spectrum Analysis</topic><topic>Technology of polymers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kumar, M. Ramesh</creatorcontrib><creatorcontrib>Merschrod S, Erika F</creatorcontrib><creatorcontrib>Poduska, Kristin M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Biomacromolecules</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kumar, M. Ramesh</au><au>Merschrod S, Erika F</au><au>Poduska, Kristin M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Correlating Mechanical Properties with Aggregation Processes in Electrochemically Fabricated Collagen Membranes</atitle><jtitle>Biomacromolecules</jtitle><addtitle>Biomacromolecules</addtitle><date>2009-07-13</date><risdate>2009</risdate><volume>10</volume><issue>7</issue><spage>1970</spage><epage>1975</epage><pages>1970-1975</pages><issn>1525-7797</issn><eissn>1526-4602</eissn><abstract>We show that mechanical stiffness is a useful metric for characterizing complex collagen assemblies, providing insight about aggregation products and pathways in collagen-based materials. This study focuses on mechanically robust collagenous membranes produced by an electrochemical synthesis process. Changing the duration of the applied electric field, or adjusting the electrolyte composition (by adding Ca2+, K+, or Na+ or by changing pH), produces membranes with a range of Young’s moduli as determined from force-displacement measurements with an atomic force microscope. The structural organization, characterized by UV−visible spectroscopy, Raman spectroscopy, optical microscopy, and atomic force microscopy, correlates with the mechanical stiffness. These data provide insights into the relative importance of different aggregation pathways enabled by our multiparameter electrochemically induced collagen assembly process.</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><pmid>19453165</pmid><doi>10.1021/bm900379g</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1525-7797 |
| ispartof | Biomacromolecules, 2009-07, Vol.10 (7), p.1970-1975 |
| issn | 1525-7797 1526-4602 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_822555761 |
| source | MEDLINE; ACS Publications |
| subjects | Applied sciences Collagen - chemistry Electrochemical Techniques Exact sciences and technology Exchange resins and membranes Forms of application and semi-finished materials Mechanical Phenomena Membranes, Artificial Microscopy, Atomic Force Natural polymers Physicochemistry of polymers Pliability Polymer industry, paints, wood Proteins Spectrum Analysis Technology of polymers |
| title | Correlating Mechanical Properties with Aggregation Processes in Electrochemically Fabricated Collagen Membranes |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T20%3A51%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Correlating%20Mechanical%20Properties%20with%20Aggregation%20Processes%20in%20Electrochemically%20Fabricated%20Collagen%20Membranes&rft.jtitle=Biomacromolecules&rft.au=Kumar,%20M.%20Ramesh&rft.date=2009-07-13&rft.volume=10&rft.issue=7&rft.spage=1970&rft.epage=1975&rft.pages=1970-1975&rft.issn=1525-7797&rft.eissn=1526-4602&rft_id=info:doi/10.1021/bm900379g&rft_dat=%3Cproquest_cross%3E822555761%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=754548660&rft_id=info:pmid/19453165&rfr_iscdi=true |