Abnormal serum IGF-II transport in non-islet cell tumor hypoglycemia results from abnormalities of both IGF binding protein-3 and acid labile subunit and leads to elevation of serum free IGF-II

The syndrome of non-islet cell tumor hypoglycemia (NICTH) is the result of hypersecretion of IGF-II by a tumor although serum IGF-II is seldom elevated. This is attributable to abnormalities of the IGF binding proteins (IGFBPs) present in NICTH which is characterized by a marked decrease in the frac...

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Veröffentlicht in:	Endocrine 1995-06, Vol.3 (6), p.425-428
Hauptverfasser:	Daughaday, W H, Trivedi, B, Baxter, R C
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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