Genetic Modeling of Primary Tooth Emergence: A Study of Australian Twins
The aim of this study was to quantify contributions of genetic and environmental factors to variation in timing of emergence of the primary teeth in a sample of monozygotic and dizygotic twins, using univariate model-fitting approaches. The sample comprised 94 pairs of monozygotic twins and 125 pair...
Gespeichert in:
| Veröffentlicht in: | Twin research and human genetics 2010-12, Vol.13 (6), p.573-581 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 581 |
|---|---|
| container_issue | 6 |
| container_start_page | 573 |
| container_title | Twin research and human genetics |
| container_volume | 13 |
| creator | Bockmann, Michelle R. Hughes, Toby E. Townsend, Grant C. |
| description | The aim of this study was to quantify contributions of genetic and environmental factors to variation in timing of emergence of the primary teeth in a sample of monozygotic and dizygotic twins, using univariate model-fitting approaches. The sample comprised 94 pairs of monozygotic twins and 125 pairs of dizygous twins, all of European ancestry, aged from 2–6 years. Tooth emergence timing was based on parental report, with a subset of data validated by clinical assessment. Heritability estimates for tooth emergence timing were generally high, around 90%, however estimates for the lower right lateral incisor and the lower canines were around 50%. These findings confirm a strong genetic influence on observed variation in the timing of emergence of the human primary teeth. |
| doi_str_mv | 10.1375/twin.13.6.573 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_822543797</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cupid>10_1375_twin_13_6_573</cupid><informt_id>10.3316/informit.596610088330326</informt_id><sourcerecordid>2789565149</sourcerecordid><originalsourceid>FETCH-LOGICAL-c584t-1301ab276eab4152608b22e47dd3f1ae6ee84bba29421edcab1ba3965928a65e3</originalsourceid><addsrcrecordid>eNptkM1v00AQxS0EoqVw5IosceDkdL8_uEWhpEhBgAgSt9XaHqcbbG_ZXQv637NuQiMhTvOk-WnmvVcULzFaYCr5ZfrlxqwWYsElfVScY0V1RQRRj-81qRiR7Kx4FuMeISqxRk-LM4IxI5qy8-J6DSMk15QffQu9G3el78rPwQ023JVb79NNeTVA2MHYwNtyWX5NU3s3M8sppmB7Z8dymy3E58WTzvYRXhznRfHt_dV2dV1tPq0_rJabquGKpQpThG1NpABbM8yJQKomBJhsW9phCwJAsbq2RDOCoW1sjWtLteCaKCs40IvizeHubfA_J4jJDC420Pd2BD9FowjhjEotM_n6H3LvpzBmc4ZIpbngmOlMVQeqCT7GAJ25PaQ3GJm5YTM3nJURJjec-VfHq1M9QPtA_600A98PQBhcMo3ve2iS82Pc2xRNBBuaG-PGzt_vfdiZ1jtj6zg_pBSL05JrITBCSlGKKBEnry4m-P3w2oYfRsjZqlh_MeuVRJhuiHmX-ctjNjvUwbU7OFXw_3R_ANQ2s5M</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2789565149</pqid></control><display><type>article</type><title>Genetic Modeling of Primary Tooth Emergence: A Study of Australian Twins</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Bockmann, Michelle R. ; Hughes, Toby E. ; Townsend, Grant C.</creator><creatorcontrib>Bockmann, Michelle R. ; Hughes, Toby E. ; Townsend, Grant C.</creatorcontrib><description>The aim of this study was to quantify contributions of genetic and environmental factors to variation in timing of emergence of the primary teeth in a sample of monozygotic and dizygotic twins, using univariate model-fitting approaches. The sample comprised 94 pairs of monozygotic twins and 125 pairs of dizygous twins, all of European ancestry, aged from 2–6 years. Tooth emergence timing was based on parental report, with a subset of data validated by clinical assessment. Heritability estimates for tooth emergence timing were generally high, around 90%, however estimates for the lower right lateral incisor and the lower canines were around 50%. These findings confirm a strong genetic influence on observed variation in the timing of emergence of the human primary teeth.</description><identifier>ISSN: 1832-4274</identifier><identifier>EISSN: 1839-2628</identifier><identifier>DOI: 10.1375/twin.13.6.573</identifier><identifier>PMID: 21142934</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Australia ; Canine teeth ; Case studies ; Child ; Child, Preschool ; Deciduous teeth ; development ; Diseases ; Environmental factors ; Female ; Genetic diversity ; genetics ; Heredity, Human ; Heritability ; Humans ; Male ; Models, Genetic ; Monozygotic twin (MZ) ; Teeth ; Tooth Eruption - genetics ; Tooth, Deciduous - physiology ; Twins ; Twins, Dizygotic - genetics ; Twins, Monozygotic - genetics</subject><ispartof>Twin research and human genetics, 2010-12, Vol.13 (6), p.573-581</ispartof><rights>Copyright © Cambridge University Press 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c584t-1301ab276eab4152608b22e47dd3f1ae6ee84bba29421edcab1ba3965928a65e3</citedby><cites>FETCH-LOGICAL-c584t-1301ab276eab4152608b22e47dd3f1ae6ee84bba29421edcab1ba3965928a65e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21142934$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bockmann, Michelle R.</creatorcontrib><creatorcontrib>Hughes, Toby E.</creatorcontrib><creatorcontrib>Townsend, Grant C.</creatorcontrib><title>Genetic Modeling of Primary Tooth Emergence: A Study of Australian Twins</title><title>Twin research and human genetics</title><addtitle>Twin Res Hum Genet</addtitle><description>The aim of this study was to quantify contributions of genetic and environmental factors to variation in timing of emergence of the primary teeth in a sample of monozygotic and dizygotic twins, using univariate model-fitting approaches. The sample comprised 94 pairs of monozygotic twins and 125 pairs of dizygous twins, all of European ancestry, aged from 2–6 years. Tooth emergence timing was based on parental report, with a subset of data validated by clinical assessment. Heritability estimates for tooth emergence timing were generally high, around 90%, however estimates for the lower right lateral incisor and the lower canines were around 50%. These findings confirm a strong genetic influence on observed variation in the timing of emergence of the human primary teeth.</description><subject>Australia</subject><subject>Canine teeth</subject><subject>Case studies</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Deciduous teeth</subject><subject>development</subject><subject>Diseases</subject><subject>Environmental factors</subject><subject>Female</subject><subject>Genetic diversity</subject><subject>genetics</subject><subject>Heredity, Human</subject><subject>Heritability</subject><subject>Humans</subject><subject>Male</subject><subject>Models, Genetic</subject><subject>Monozygotic twin (MZ)</subject><subject>Teeth</subject><subject>Tooth Eruption - genetics</subject><subject>Tooth, Deciduous - physiology</subject><subject>Twins</subject><subject>Twins, Dizygotic - genetics</subject><subject>Twins, Monozygotic - genetics</subject><issn>1832-4274</issn><issn>1839-2628</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNptkM1v00AQxS0EoqVw5IosceDkdL8_uEWhpEhBgAgSt9XaHqcbbG_ZXQv637NuQiMhTvOk-WnmvVcULzFaYCr5ZfrlxqwWYsElfVScY0V1RQRRj-81qRiR7Kx4FuMeISqxRk-LM4IxI5qy8-J6DSMk15QffQu9G3el78rPwQ023JVb79NNeTVA2MHYwNtyWX5NU3s3M8sppmB7Z8dymy3E58WTzvYRXhznRfHt_dV2dV1tPq0_rJabquGKpQpThG1NpABbM8yJQKomBJhsW9phCwJAsbq2RDOCoW1sjWtLteCaKCs40IvizeHubfA_J4jJDC420Pd2BD9FowjhjEotM_n6H3LvpzBmc4ZIpbngmOlMVQeqCT7GAJ25PaQ3GJm5YTM3nJURJjec-VfHq1M9QPtA_600A98PQBhcMo3ve2iS82Pc2xRNBBuaG-PGzt_vfdiZ1jtj6zg_pBSL05JrITBCSlGKKBEnry4m-P3w2oYfRsjZqlh_MeuVRJhuiHmX-ctjNjvUwbU7OFXw_3R_ANQ2s5M</recordid><startdate>20101201</startdate><enddate>20101201</enddate><creator>Bockmann, Michelle R.</creator><creator>Hughes, Toby E.</creator><creator>Townsend, Grant C.</creator><general>Cambridge University Press</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20101201</creationdate><title>Genetic Modeling of Primary Tooth Emergence: A Study of Australian Twins</title><author>Bockmann, Michelle R. ; Hughes, Toby E. ; Townsend, Grant C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c584t-1301ab276eab4152608b22e47dd3f1ae6ee84bba29421edcab1ba3965928a65e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Australia</topic><topic>Canine teeth</topic><topic>Case studies</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Deciduous teeth</topic><topic>development</topic><topic>Diseases</topic><topic>Environmental factors</topic><topic>Female</topic><topic>Genetic diversity</topic><topic>genetics</topic><topic>Heredity, Human</topic><topic>Heritability</topic><topic>Humans</topic><topic>Male</topic><topic>Models, Genetic</topic><topic>Monozygotic twin (MZ)</topic><topic>Teeth</topic><topic>Tooth Eruption - genetics</topic><topic>Tooth, Deciduous - physiology</topic><topic>Twins</topic><topic>Twins, Dizygotic - genetics</topic><topic>Twins, Monozygotic - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bockmann, Michelle R.</creatorcontrib><creatorcontrib>Hughes, Toby E.</creatorcontrib><creatorcontrib>Townsend, Grant C.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Twin research and human genetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bockmann, Michelle R.</au><au>Hughes, Toby E.</au><au>Townsend, Grant C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genetic Modeling of Primary Tooth Emergence: A Study of Australian Twins</atitle><jtitle>Twin research and human genetics</jtitle><addtitle>Twin Res Hum Genet</addtitle><date>2010-12-01</date><risdate>2010</risdate><volume>13</volume><issue>6</issue><spage>573</spage><epage>581</epage><pages>573-581</pages><issn>1832-4274</issn><eissn>1839-2628</eissn><abstract>The aim of this study was to quantify contributions of genetic and environmental factors to variation in timing of emergence of the primary teeth in a sample of monozygotic and dizygotic twins, using univariate model-fitting approaches. The sample comprised 94 pairs of monozygotic twins and 125 pairs of dizygous twins, all of European ancestry, aged from 2–6 years. Tooth emergence timing was based on parental report, with a subset of data validated by clinical assessment. Heritability estimates for tooth emergence timing were generally high, around 90%, however estimates for the lower right lateral incisor and the lower canines were around 50%. These findings confirm a strong genetic influence on observed variation in the timing of emergence of the human primary teeth.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>21142934</pmid><doi>10.1375/twin.13.6.573</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1832-4274 |
| ispartof | Twin research and human genetics, 2010-12, Vol.13 (6), p.573-581 |
| issn | 1832-4274 1839-2628 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_822543797 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Australia Canine teeth Case studies Child Child, Preschool Deciduous teeth development Diseases Environmental factors Female Genetic diversity genetics Heredity, Human Heritability Humans Male Models, Genetic Monozygotic twin (MZ) Teeth Tooth Eruption - genetics Tooth, Deciduous - physiology Twins Twins, Dizygotic - genetics Twins, Monozygotic - genetics |
| title | Genetic Modeling of Primary Tooth Emergence: A Study of Australian Twins |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T05%3A37%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Genetic%20Modeling%20of%20Primary%20Tooth%20Emergence:%20A%20Study%20of%20Australian%20Twins&rft.jtitle=Twin%20research%20and%20human%20genetics&rft.au=Bockmann,%20Michelle%20R.&rft.date=2010-12-01&rft.volume=13&rft.issue=6&rft.spage=573&rft.epage=581&rft.pages=573-581&rft.issn=1832-4274&rft.eissn=1839-2628&rft_id=info:doi/10.1375/twin.13.6.573&rft_dat=%3Cproquest_cross%3E2789565149%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2789565149&rft_id=info:pmid/21142934&rft_cupid=10_1375_twin_13_6_573&rft_informt_id=10.3316/informit.596610088330326&rfr_iscdi=true |